Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.51 |
| ▸ | HSD17B1 | P14061 | 6/20 | 0.48 |
| ▸ | HSD17B2 | P37059 | 5/20 | 0.48 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL767555 | 0.95 | NR1H4 (0.55) | NR1H4SENP1KMT2ALMNAESR1 | |
| SCHEMBL12332903 | 0.90 | HSD17B1 (0.47) | NR1H4HSD17B1HSD17B2SENP1KMT2A | |
| SCHEMBL17826637 | 0.87 | SENP1 (0.46) | NR1H4HSD17B1SENP1KMT2ALMNA | |
| SCHEMBL19621079 | 0.86 | KMT2A (0.58) | NR1H4KMT2ALMNAESR1ESR2 | |
| SCHEMBL767642 | 0.86 | KMT2A (0.50) | NR1H4KMT2ALMNAESR1CA12 | |
| SCHEMBL767373 | 0.85 | NR1H4 (0.54) | NR1H4KMT2ALMNAESR1CA12 | |
| SCHEMBL19630948 | 0.84 | NR1H4 (0.54) | NR1H4KMT2ALMNAESR1CA1 | |
| SCHEMBL31574453 | 0.84 | CA12 (0.46) | NR1H4SENP1KMT2AESR1CA12 | |
| SCHEMBL31574446 | 0.84 | CA12 (0.46) | NR1H4SENP1KMT2AESR1CA12 | |
| SCHEMBL15290365 | 0.84 | SMN1; SMN2 (0.56) | NR1H4SENP1KMT2ALMNAESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8404794-B2 | Liquid crystal compositions | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-03-26 | — | — | US | disclosed |
| US-8344175-B2 | Liquid crystal compositions, polymer networks derived therefrom and process for making the same | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-01-01 | — | — | US | disclosed |
| US-20120104316-A1 | LIQUID CRYSTAL COMPOSITIONS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-05-03 | — | — | US | disclosed |
| EP-2440631-A1 | LIQUID CRYSTAL COMPOSITIONS | E. I. du Pont de Nemours and Company (US) | 2012-04-18 | — | — | EP | disclosed |
| EP-2440632-A2 | LIQUID CRYSTAL COMPOSITIONS | E. I. du Pont de Nemours and Company (US) | 2012-04-18 | — | — | EP | disclosed |
| US-20120068116-A1 | LIQUID CRYSTAL COMPOSITIONS | E.I.DU PONT DE NEMOURS AND COMPANY (US) | 2012-03-22 | — | — | US | disclosed |
| US-20120071618-A1 | LIQUID CRYSTAL COMPOSITIONS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-03-22 | — | — | US | disclosed |
| US-8067068-B2 | Liquid crystal compositions | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-11-29 | — | — | US | disclosed |
| US-8044228-B2 | Liquid crystal compositions | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-10-25 | — | — | US | disclosed |
| US-8034255-B2 | Liquid crystal compositions | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-10-11 | — | — | US | disclosed |
| US-7879256-B2 | bis(meth)acrylates with esters linking mesogen to a flexible spacer and polymerizable (meth)acrylates | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-02-01 | — | — | US | disclosed |
| WO-2010144411-A1 | LIQUID CRYSTAL COMPOSITIONS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-12-16 | — | — | WO | disclosed |
| WO-2010144393-A2 | LIQUID CRYSTAL COMPOSITIONS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-12-16 | — | — | WO | disclosed |
| US-20100308270-A1 | LIQUID CRYSTAL COMPOSTIONS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-12-09 | — | — | US | disclosed |
| US-20100308269-A1 | LIQUID CRYSTAL COMPOSITIONS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-12-09 | — | — | US | disclosed |
| US-20100308268-A1 | LIQUID CRYSTAL COMPOSITIONS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-12-09 | — | — | US | disclosed |
| US-20100308265-A1 | LIQUID CRYSTAL COMPOSITIONS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-12-09 | — | — | US | disclosed |
| EP-2001974-A1 | LIQUID CRYSTAL COMPOSITIONS, POLYMER NETWORKS DERIVED THEREFROM AND PROCESS FOR MAKING THE SAME | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-12-17 | — | — | EP | disclosed |
| WO-2007120458-A1 | LIQUID CRYSTAL COMPOSITIONS, POLYMER NETWORKS DERIVED THEREFROM AND PROCESS FOR MAKING THE SAME | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-10-25 | — | — | WO | disclosed |
| US-20070228326-A1 | Liquid crystal compositions, polymer networks derived therefrom and process for making the same | E. I. DU PONT DE NEMOURS AND COMPANY | 2007-10-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100308265-A1 | LIQUID CRYSTAL COMPOSITIONS | CNOT9, AQP3, AQP1 | NR1H4 4058/4885HSD17B1 3379/4885HSD17B2 2899/4885 |
| US-20100308270-A1 | LIQUID CRYSTAL COMPOSTIONS | TTR, CNOT9, CNOT7 | NR1H4 3771/4885HSD17B1 1803/4885HSD17B2 1955/4885 |
| US-20120068116-A1 | LIQUID CRYSTAL COMPOSITIONS | AQP3, AQP1, NCAPD2 | NR1H4 2923/4885HSD17B1 1185/4885HSD17B2 991/4885 |
| US-20120071618-A1 | LIQUID CRYSTAL COMPOSITIONS | CNOT9, AQP3, AQP1 | NR1H4 4058/4885HSD17B1 3379/4885HSD17B2 2899/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.