Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11531757 | 0.85 | KMT2A (0.35) | TSHRKMT2AKDM4EATM | |
| SCHEMBL7679328 | 0.78 | KMT2A (0.41) | KMT2AKDM4EMEN1LMNACASP1 | |
| SCHEMBL8090075 | 0.78 | TSHR (0.39) | TSHRKMT2AKDM4EATM | |
| SCHEMBL7819515 | 0.71 | HTR2A (0.39) | TSHRKDM4ELMNA | |
| SCHEMBL13159374 | 0.71 | TRPA1 (0.44) | LMNA | |
| SCHEMBL9090435 | 0.71 | CES2 (0.33) | TSHRKMT2AKDM4ELMNAATM | |
| SCHEMBL8090152 | 0.71 | KMT2A (0.33) | TSHRKMT2AKDM4EATM | |
| SCHEMBL9384051 | 0.71 | DPP4 (0.39) | KMT2AATM | |
| SCHEMBL9090443 | 0.71 | SMN1; SMN2 (0.46) | KDM4ELMNA | |
| Hydrochloric Acid SCHEMBL9985742 | 0.69 | DPP4 (0.38) | KMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0135814-A1 | 1-(1H-tetrazol-5-ylalkoxy)-2-azetidinones | E.R. Squibb & Sons, Inc. (US) | 1985-04-03 | — | — | EP | disclosed |