Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6657656 | 0.86 | ITGA4 (0.41) | MAPTSMN1; SMN2HTTLMNAGRIN2B | |
| SCHEMBL6633696 | 0.74 | MEN1 (0.61) | GRIN2BMEN1KMT2AMAPK1ALDH1A1 | |
| SCHEMBL6633642 | 0.73 | FNTA (0.44) | FAAHMGLL | |
| SCHEMBL6615155 | 0.73 | FNTA (0.44) | FAAHMGLL | |
| SCHEMBL6615906 | 0.73 | MEN1 (0.60) | GRIN2BMEN1KMT2AMAPK1ALDH1A1 | |
| SCHEMBL28474456 | 0.72 | CMA1 (0.42) | — | |
| SCHEMBL6614346 | 0.69 | NR1H2 (0.44) | MEN1KMT2AMAPK1 | |
| SCHEMBL27873428 | 0.69 | CA1 (0.49) | MAPTSMN1; SMN2HTTLMNAMAPK1 | |
| SCHEMBL5068055 | 0.69 | MTNR1A (0.40) | MAPTMEN1KMT2AMAPK1 | |
| SCHEMBL11890095 | 0.69 | MTNR1A (0.40) | MAPTMEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6455523-B1 | ADMINISTERING 1,4-BENZODIAZEPINE DERIVATIVE AS ANTITUMOR OR ANTICARCINOGENIC AGENT | BRISTOL-MYERS SQUIBB COMPANY | 2002-09-24 | — | — | US | disclosed |