Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 2/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.42 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.42 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.42 |
| ▸ | GSTP1 | P09211 | 10/20 | 0.41 |
| ▸ | GSTM2 | P28161 | 9/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MYC | P01106 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7714790 | 0.75 | GSTP1 (0.54) | GSTP1GSTM2MEN1KMT2AMYC | |
| SCHEMBL21148811 | 0.74 | GSTP1 (0.41) | GSTP1GSTM2MEN1KMT2ANPC1 | |
| SCHEMBL10089701 | 0.73 | GSTM2 (0.56) | GSTP1GSTM2MEN1KMT2ANPC1 | |
| SCHEMBL9102043 | 0.71 | GSTM2 (0.44) | S1PR1S1PR3S1PR5S1PR4GSTP1 | |
| SCHEMBL7052057 | 0.69 | GSTM2 (0.66) | GSTP1GSTM2MEN1KMT2AMYC | |
| SCHEMBL8788825 | 0.69 | GSTM2 (0.51) | GSTP1GSTM2MEN1KMT2AMYC | |
| SCHEMBL25868523 | 0.68 | GSTM2 (0.51) | GSTP1GSTM2MEN1KMT2ANPC1 | |
| SCHEMBL9100736 | 0.68 | GSTP1 (0.43) | S1PR1S1PR3S1PR5S1PR4GSTP1 | |
| SCHEMBL2608494 | 0.65 | GSTP1 (0.61) | GSTP1GSTM2MEN1KMT2AMYC | |
| SCHEMBL3501548 | 0.65 | MEN1 (0.60) | GSTP1GSTM2MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002072025-A2 | IMPROVING POSTSYNAPTIC RESPONSE BY A COMBINATION OF 4-MINOPYRIDINE AND AGONIST | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF HEALTH AND HUMAN SERVICES (US) | 2002-09-19 | — | — | WO | disclosed |