SCHEMBL21148811

SCHEMBL21148811

O=[N+]([O-])c1ccc(CCCCCCCc2c[nH]nn2)c2nonc12

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GSTP1 P09211 12/20 0.41
GSTM2 P28161 11/20 0.41
IDO1 P14902 4/20 0.39
MEN1 O00255 4/20 0.38
KMT2A Q03164 4/20 0.38
USP2 O75604 2/20 0.38
HTT P42858 1/20 0.38
RECQL P46063 1/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
POLB P06746 1/20 0.38
TNNI3 P19429 1/20 0.38
TNNT2 P45379 1/20 0.38
TNNC1 P63316 1/20 0.38
MYC P01106 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7714790 0.76 GSTP1 (0.54) GSTP1GSTM2MEN1KMT2AUSP2
SCHEMBL7679904 0.74 S1PR1 (0.42) GSTP1GSTM2IDO1MEN1KMT2A
SCHEMBL9102043 0.72 GSTM2 (0.44) GSTP1GSTM2IDO1MEN1KMT2A
SCHEMBL10089701 0.71 GSTM2 (0.56) GSTP1GSTM2IDO1MEN1KMT2A
SCHEMBL7052057 0.70 GSTM2 (0.66) GSTP1GSTM2IDO1MEN1KMT2A
SCHEMBL8788825 0.70 GSTM2 (0.51) GSTP1GSTM2IDO1MEN1KMT2A
SCHEMBL9100736 0.69 GSTP1 (0.43) GSTP1GSTM2MEN1KMT2AMYC
SCHEMBL28396262 0.68 L3MBTL1 (0.34)
SCHEMBL20873298 0.67 OGA (0.40) GSTP1GSTM2
SCHEMBL25868523 0.66 GSTM2 (0.51) GSTP1GSTM2IDO1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210401946-A1 CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN SANOFI (FR) 2021-12-30 US disclosed
US-20210401947-A1 CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN SANOFI (FR) 2021-12-30 US disclosed
US-11090364-B2 Conjugates of a pharmaceutical agent and a moiety capable of binding to a glucose sensing protein SANOFI (FR) 2021-08-17 US disclosed
US-20190209656-A1 CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN SANOFI (FR) 2019-07-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11090364-B2 Conjugates of a pharmaceutical agent and a moiety capable of binding to a glucose sensing protein GPR119, SLC2A8, SLC2A4 GSTP1 1317/4885GSTM2 2587/4885IDO1 4450/4885
US-20190209656-A1 CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN GPR119, SLC2A8, SLC2A4 GSTP1 1317/4885GSTM2 2587/4885IDO1 4450/4885
US-20210401946-A1 CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN GPR119, SLC2A8, SLC2A4 GSTP1 1317/4885GSTM2 2587/4885IDO1 4450/4885
US-20210401947-A1 CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN GPR119, SLC2A8, SLC2A4 GSTP1 1317/4885GSTM2 2587/4885IDO1 4450/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.