Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.37 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | PNMT | P11086 | 1/20 | 0.36 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.35 |
| ▸ | CACNB1 | Q02641 | 2/20 | 0.35 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6487215 | 0.90 | ALDH1A1 (0.42) | ALDH1A1GAACYP3A4LMNA | |
| SCHEMBL6487800 | 0.85 | CNR1 (0.38) | MEN1KMT2ATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL6479396 | 0.82 | L3MBTL1 (0.36) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL6479354 | 0.81 | MAPT (0.39) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL7684336 | 0.80 | ALDH1A1 (0.40) | POLBMAPTALDH1A1GAACYP3A4 | |
| SCHEMBL7687237 | 0.80 | CNR1 (0.43) | MAPTALDH1A1CYP3A4 | |
| SCHEMBL7431251 | 0.80 | MAPT (0.45) | MEN1KMT2AMAPT | |
| SCHEMBL7686449 | 0.80 | CYP2C19 (0.41) | MEN1KMT2AMAPTALDH1A1CYP1A2 | |
| SCHEMBL6477248 | 0.79 | CYP2C9 (0.45) | KMT2AMAPTALDH1A1CYP3A4LMNA | |
| SCHEMBL6492632 | 0.79 | ALDH1A1 (0.40) | POLBMAPTALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492392-B1 | INHIBITING TUMOR CELL PROLIFERATION | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2002-12-10 | — | — | US | disclosed |
| WO-2001085716-A1 | 2-PIPERIDONE COMPOUNDS FOR THE TREATMENT OF CANCER | KYOWA HAKKO KOGYO CO., LTD (JP) | 2001-11-15 | — | — | WO | disclosed |