Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CTSA | P10619 | 3/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8177147 | 0.93 | MEN1 (0.34) | SMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL7675970 | 0.92 | CASP1 (0.36) | CTSAMEN1NPC1RAB9AKMT2A | |
| SCHEMBL7684625 | 0.90 | CASP1 (0.34) | CTSAIDO1MEN1KMT2A | |
| SCHEMBL7677990 | 0.90 | ALDH1A1 (0.38) | SMN1; SMN2ALDH1A1GPR139POLBMAPT | |
| SCHEMBL7686237 | 0.88 | RAB9A (0.35) | ALDH1A1RECQLPOLBMAPTMEN1 | |
| SCHEMBL7686539 | 0.87 | CTSA (0.34) | SMN1; SMN2ALDH1A1CTSARECQLMAPT | |
| SCHEMBL7678033 | 0.86 | CASP1 (0.36) | — | |
| SCHEMBL7679637 | 0.86 | MAPT (0.34) | SMN1; SMN2ALDH1A1CTSARECQLMAPT | |
| SCHEMBL7679529 | 0.85 | TP53 (0.36) | SMN1; SMN2CTSAPOLBMEN1KMT2A | |
| SCHEMBL7679414 | 0.85 | ALDH1A1 (0.41) | SMN1; SMN2ALDH1A1CTSAGPR139IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6136834-A | TETRAZOLE PEPTIDES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2000-10-24 | — | — | US | claimed |
| EP-0900791-A1 | TETRAZOLE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-03-10 | — | — | EP | claimed |
| US-6376484-B1 | FOR PREVENTION AND/OR TREATMENT OF VARIOUS KINDS OF INFLAMMATORY DISEASE | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-04-23 | — | — | US | disclosed |
| US-6136834-A | TETRAZOLE PEPTIDES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2000-10-24 | — | — | US | disclosed |
| EP-0900791-A1 | TETRAZOLE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-03-10 | — | — | EP | disclosed |