Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | CNKSR1 | Q969H4 | 1/20 | 0.34 |
| ▸ | OGT | O15294 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 6/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 2/20 | 0.32 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.32 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7675970 | 0.91 | CASP1 (0.36) | RAB9AMEN1KMT2ANPC1TP53 | |
| SCHEMBL7684625 | 0.90 | CASP1 (0.34) | MEN1KMT2ATP53CASP3ITGB1 | |
| SCHEMBL7680229 | 0.88 | SMN1; SMN2 (0.39) | RAB9AMEN1KMT2ANPC1POLB | |
| SCHEMBL8177147 | 0.86 | MEN1 (0.34) | MEN1KMT2AALDH1A1 | |
| SCHEMBL7684507 | 0.85 | MTNR1A (0.33) | RAB9ANPC1MAPTALDH1A1TP53 | |
| SCHEMBL7683953 | 0.85 | ALDH1A1 (0.40) | RAB9AMEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL7678033 | 0.85 | CASP1 (0.36) | TP53CASP3 | |
| SCHEMBL7679637 | 0.85 | MAPT (0.34) | RAB9AMEN1KMT2ANPC1MAPT | |
| SCHEMBL7679529 | 0.85 | TP53 (0.36) | MEN1KMT2APOLBTP53CASP3 | |
| SCHEMBL7678054 | 0.84 | USP2 (0.35) | RAB9AMEN1KMT2ANPC1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6136834-A | TETRAZOLE PEPTIDES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2000-10-24 | — | — | US | claimed |
| EP-0900791-A1 | TETRAZOLE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-03-10 | — | — | EP | claimed |
| US-6376484-B1 | FOR PREVENTION AND/OR TREATMENT OF VARIOUS KINDS OF INFLAMMATORY DISEASE | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-04-23 | — | — | US | disclosed |
| US-6136834-A | TETRAZOLE PEPTIDES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2000-10-24 | — | — | US | disclosed |
| EP-0900791-A1 | TETRAZOLE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-03-10 | — | — | EP | disclosed |