Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ACP3 | P15309 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6903550 | 0.88 | MEN1 (0.50) | MEN1KMT2AALDH1A1HTTL3MBTL1 | |
| SCHEMBL6905899 | 0.88 | MEN1 (0.50) | MEN1KMT2AALDH1A1HTTL3MBTL1 | |
| SCHEMBL7680353 | 0.86 | F2 (0.42) | MEN1KMT2AALDH1A1LMNAHPGD | |
| SCHEMBL7688540 | 0.85 | L3MBTL1 (0.48) | MEN1KMT2AL3MBTL1 | |
| SCHEMBL7682611 | 0.85 | F2 (0.41) | ALDH1A1HTTMAPTCYP2C19KDM4E | |
| SCHEMBL30947796 | 0.85 | ALDH1A1 (0.41) | MEN1KMT2AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL6478745 | 0.85 | ALDH1A1 (0.41) | MEN1KMT2AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL6478160 | 0.85 | KCNA5 (0.44) | MEN1KMT2AALDH1A1L3MBTL1LMNA | |
| SCHEMBL698333 | 0.84 | ALDH1A1 (0.51) | KMT2AALDH1A1MAPTHPGDCYP3A4 | |
| SCHEMBL29921355 | 0.84 | ALDH1A1 (0.51) | KMT2AALDH1A1MAPTHPGDCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492392-B1 | INHIBITING TUMOR CELL PROLIFERATION | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2002-12-10 | — | — | US | disclosed |
| WO-2001085716-A1 | 2-PIPERIDONE COMPOUNDS FOR THE TREATMENT OF CANCER | KYOWA HAKKO KOGYO CO., LTD (JP) | 2001-11-15 | — | — | WO | disclosed |