Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP1LC3B | Q9GZQ8 | 2/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 2/20 | 0.31 |
| ▸ | RBP4 | P02753 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7690067 | 0.85 | MAP1LC3B (0.38) | MAP1LC3BLMNAHTR2CRBP4 | |
| SCHEMBL7686913 | 0.82 | LMNA (0.48) | MAP1LC3BLMNA | |
| SCHEMBL7683611 | 0.81 | MAP1LC3B (0.49) | MAP1LC3BBRD4LMNA | |
| SCHEMBL7680946 | 0.78 | HTR2C (0.40) | LMNAHTR2CRBP4 | |
| SCHEMBL7689364 | 0.77 | MAPT (0.47) | MAP1LC3BLMNA | |
| SCHEMBL7687262 | 0.75 | ALPL (0.43) | MAP1LC3BLMNA | |
| SCHEMBL7681124 | 0.68 | MAP1LC3B (0.42) | MAP1LC3BLMNAHTR2C | |
| SCHEMBL7683976 | 0.68 | MAP1LC3B (0.41) | MAP1LC3BLMNA | |
| SCHEMBL28571106 | 0.66 | BRD4 (0.56) | MAP1LC3BBRD4LMNAHTR2C | |
| SCHEMBL657211 | 0.65 | BRD4 (0.51) | MAP1LC3BBRD4LMNAHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6350749-B1 | SODIUM CHANNEL MODULATORS, ANTIARRHYTHMIA AND HYPOTENSIVE AGENTS; CARDIOVASCULAR DISORDERS, ANGINA PECTORIS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-02-26 | — | — | US | disclosed |
| EP-1057812-A1 | AMINOGUANIDINE HYDRAZONE DERIVATIVES, PROCESS FOR PRODUCING THE SAME AND DRUGS THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2000-12-06 | — | — | EP | disclosed |