Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 14/20 | 0.59 |
| ▸ | ADAM17 | P78536 | 9/20 | 0.59 |
| ▸ | MMP2 | P08253 | 9/20 | 0.56 |
| ▸ | MMP14 | P50281 | 4/20 | 0.56 |
| ▸ | MMP1 | P03956 | 7/20 | 0.55 |
| ▸ | MMP9 | P14780 | 3/20 | 0.53 |
| ▸ | MMP3 | P08254 | 1/20 | 0.53 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6788797 | 0.91 | MMP13 (0.71) | MMP13ADAM17MMP2MMP14MMP1 | |
| SCHEMBL5919696 | 0.82 | MMP13 (0.69) | MMP13ADAM17MMP2MMP14MMP1 | |
| SCHEMBL7681442 | 0.79 | MMP1 (0.55) | MMP13ADAM17MMP2MMP14MMP1 | |
| SCHEMBL6784917 | 0.79 | MMP13 (0.54) | MMP13ADAM17MMP2MMP14MMP1 | |
| SCHEMBL6791077 | 0.76 | ADAM17 (0.68) | MMP13ADAM17MMP2MMP14MMP1 | |
| SCHEMBL3946150 | 0.75 | ADAM17 (1.00) | MMP13ADAM17MMP2MMP14MMP1 | |
| SCHEMBL10021361 | 0.73 | MMP13 (0.72) | MMP13ADAM17MMP2MMP14MMP1 | |
| SCHEMBL29227450 | 0.72 | KMT2A (0.48) | MMP13ADAM17MMP2MMP14GPR119 | |
| SCHEMBL4978176 | 0.72 | GPR119 (0.54) | GPR119 | |
| SCHEMBL4975111 | 0.72 | GPR119 (0.54) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6476027-B1 | N-hydroxy 4-sulfonyl butanamide compounds | MONSANTO COMPANY | 2002-11-05 | — | — | US | disclosed |