Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.42 |
| ▸ | APP | P05067 | 4/20 | 0.40 |
| ▸ | MET | P08581 | 9/20 | 0.39 |
| ▸ | AKR1B10 | O60218 | 3/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA4 | P22748 | 2/20 | 0.36 |
| ▸ | CA6 | P23280 | 2/20 | 0.36 |
| ▸ | CA5A | P35218 | 2/20 | 0.36 |
| ▸ | CA7 | P43166 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3951413 | 0.94 | MET (0.41) | ALOX5APPMETAKR1B10AKR1B1 | |
| SCHEMBL22129610 | 0.86 | APP (0.49) | ALOX5APPMETAKR1B10AKR1B1 | |
| SCHEMBL21693917 | 0.85 | APP (0.42) | ALOX5APPMETAKR1B10AKR1B1 | |
| SCHEMBL3956215 | 0.83 | MET (0.36) | ALOX5APPMETAKR1B10AKR1B1 | |
| SCHEMBL3949048 | 0.82 | SMN1; SMN2 (0.39) | APPSMN1; SMN2 | |
| SCHEMBL20494449 | 0.82 | NPC1 (0.34) | METAKR1B10AKR1B1CA12CA4 | |
| SCHEMBL5693426 | 0.81 | FFAR4 (0.33) | ALOX5APPCYP3A4MEN1LMNA | |
| SCHEMBL25409102 | 0.81 | APP (0.36) | ALOX5APPMETAKR1B10AKR1B1 | |
| SCHEMBL5693422 | 0.81 | RAF1 (0.32) | ALOX5APPMEN1LMNAKMT2A | |
| SCHEMBL7144226 | 0.81 | ALOX5 (0.35) | ALOX5METAKR1B10AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6451887-B1 | Benzotriazoles containing α-cumyl groups substituted by heteroatoms and compositions stabilized therewith | CIBA SPECIALTY CHEMICALS CORPORATION | 2002-09-17 | — | — | US | disclosed |