Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 3/20 | 0.36 |
| ▸ | ASAH1 | Q13510 | 2/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | RAF1 | P04049 | 3/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | TYR | P14679 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
| ▸ | ESRRG | P62508 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3949720 | 0.90 | GAA (0.41) | ASAH1MTNR1AMTNR1BRAF1FAAH | |
| SCHEMBL3949046 | 0.86 | MTNR1A (0.38) | SMN1; SMN2ASAH1MTNR1AMTNR1BRAF1 | |
| SCHEMBL7145809 | 0.86 | GAA (0.47) | SMN1; SMN2NAMPTASAH1ACHEBCHE | |
| SCHEMBL3951413 | 0.84 | MET (0.41) | APP | |
| SCHEMBL7681875 | 0.82 | ALOX5 (0.42) | SMN1; SMN2APP | |
| SCHEMBL27466288 | 0.81 | NPC1 (0.39) | SMN1; SMN2 | |
| SCHEMBL3949043 | 0.80 | TMEM97 (0.34) | SMN1; SMN2MTNR1AMTNR1BRAF1 | |
| SCHEMBL2638762 | 0.80 | NPC1 (0.37) | — | |
| SCHEMBL5834556 | 0.79 | KAT8 (0.41) | ACHE | |
| SCHEMBL5693442 | 0.79 | FFAR4 (0.40) | RAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6391949-B1 | — | — | None | — | — | US | claimed |
| US-6800676-B2 | ULTRAVIOLET RADIATION ABSORBERS; HEAT AND OXIDATION RESISTANCE | CIBA SPECIALTY CHEMICALS CORPORATION | 2004-10-05 | — | — | US | claimed |
| US-6677392-B2 | USED TO STABILIE NATURAL, SEMI-SYNTHETIC OR SYNTHETIC POLYMER. | CIBA SPECIALTY CHEMICALS CORPORATION | 2004-01-13 | — | — | US | claimed |
| US-6638997-B2 | Used for stabilizing polyolefin and automotive coating formulation against the deleterious effects of oxidative, thermal and actinic radiation | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-10-28 | — | — | US | claimed |
| US-6605727-B2 | Processes for the preparation of benzotriazole UV absorbers | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-08-12 | — | — | US | claimed |
| US-20030130524-A1 | Processes for the preparation of benzotriazole UV absorbers | WOOD MERVIN G (US) | 2003-07-10 | — | — | US | claimed |
| US-6586507-B2 | For stabilizing polyolefins, especially thermoplastic polyolefins, against the deleterious effects of oxidative, thermal and actinic radiation, also for stabilizing acid catalyzed and ambient cured coatings systems | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-07-01 | — | — | US | claimed |
| US-20030120083-A1 | Processes for the preparation of benzotriazole UV absorbers | WOOD MERVIN G (US) | 2003-06-26 | — | — | US | claimed |
| US-20030120077-A1 | Hydroxy substituted N-alkoxy hindered amines and compositions stabilized therewith | GALBO JAMES PETER (US) | 2003-06-26 | — | — | US | claimed |
| US-20030004235-A1 | Benzotriazoles containing phenyl groups substituted by heteroatoms and compositions stabilized therewith | CIBA SPECIALTY CHEMICALS CORP. | 2003-01-02 | — | — | US | claimed |
| US-6403681-B2 | STABILIZER FOR PLASTICS | CIBA SPECIALTY CHEMICALS CORPORATION | 2002-06-11 | — | — | US | claimed |
| US-20020065341-A1 | Benzotriazole UV absorbers having enhanced durability | RAVICHANDRAN RAMANATHAN (US) | 2002-05-30 | — | — | US | claimed |
| US-6391949-B2 | FOR AUTOMOBILE FINISHES; HEAT, OXIDATION, RADIATION RESISTANCE | CIBA SPECIALTY CHEMICALS CORPORATION | 2002-05-21 | — | — | US | claimed |
| US-6376584-B1 | OXIDATION RESISTANCE, HEAT RESISTANCE, PHOTOSTABILITY | CIBA SPECIALTY CHEMICALS CORPORATION | 2002-04-23 | — | — | US | claimed |
| US-20020035175-A1 | Processes for the preparation of benzotriazole UV absorbers | CIBA SPECIALTY CHEMICALS CORP. | 2002-03-21 | — | — | US | claimed |
| US-6353113-B1 | DIAZOTIZING THE PERFLUOROALKYL SUBSTITUTED O-NITROANILINE WITH SULFURIC ACID AND SODIUM NITRITE OR NITROSYLSULFURIC ACID TO FORM THE CORRESPONDING MONOAZOBENZENE INTERMEDIATE VIA THE DIAZONIUM SALT INTERMEDIATE WHICH IS THEN REDUCED | CIBA SPECIALTY CHEMICALS CORPORATION | 2002-03-05 | — | — | US | claimed |
| US-20010031872-A1 | Hydroxy-substituted N-Alkoxy hindered amines and compositions stabilized therewith | GALBO JAMES P (US) | 2001-10-18 | — | — | US | claimed |
| US-6296674-B1 | Candle wax stabilized with red-shift benzotriazoles | CIBA SPECIALTY CHEMICALS CORPORATION | 2001-10-02 | — | — | US | claimed |
| US-20010018520-A1 | Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith | GALBO JAMES P (US) | 2001-08-30 | — | — | US | claimed |
| US-6262151-B1 | FOR AUTOMOTIVE COATINGS | CIBA SPECIALTY CHEMICALS CORPORATION | 2001-07-17 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020035175-A1 | Processes for the preparation of benzotriazole UV absorbers | SULT1A1, SULT2A1, NISCH | SMN1; SMN2 3035/4885NAMPT 67/4885ASAH1 4577/4885 |
| US-20030120083-A1 | Processes for the preparation of benzotriazole UV absorbers | SULT1A1, SULT2A1, NISCH | SMN1; SMN2 3035/4885NAMPT 67/4885ASAH1 4577/4885 |
| US-20030130524-A1 | Processes for the preparation of benzotriazole UV absorbers | SULT1A1, SULT2A1, NISCH | SMN1; SMN2 3035/4885NAMPT 67/4885ASAH1 4577/4885 |
| US-20030004235-A1 | Benzotriazoles containing phenyl groups substituted by heteroatoms and compositions stabilized therewith | SUV39H1, SUV39H2, TPST2 | SMN1; SMN2 2918/4885NAMPT 943/4885ASAH1 4458/4885 |
| US-20030120077-A1 | Hydroxy substituted N-alkoxy hindered amines and compositions stabilized therewith | OGG1, POLH, OGFOD1 | SMN1; SMN2 552/4885NAMPT 2130/4885ASAH1 640/4885 |
| US-20010018520-A1 | Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith | POLH, OGG1, OGFOD1 | SMN1; SMN2 595/4885NAMPT 2541/4885ASAH1 520/4885 |
| US-20010031872-A1 | Hydroxy-substituted N-Alkoxy hindered amines and compositions stabilized therewith | POLH, OGG1, OGFOD1 | SMN1; SMN2 595/4885NAMPT 2541/4885ASAH1 520/4885 |
| US-20020065341-A1 | Benzotriazole UV absorbers having enhanced durability | TERT, AHR, ARNT | SMN1; SMN2 2440/4885NAMPT 3475/4885ASAH1 4828/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.