Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | F10 | P00742 | 4/20 | 0.53 |
| ▸ | F2 | P00734 | 1/20 | 0.53 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.51 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.51 |
| ▸ | SRC | P12931 | 1/20 | 0.48 |
| ▸ | CCR2 | P41597 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6741019 | 0.89 | MEN1 (0.47) | KMT2AMEN1F10F2NOD2 | |
| SCHEMBL7682421 | 0.88 | MTNR1A (0.51) | KMT2AMEN1F10F2NOD2 | |
| SCHEMBL3960725 | 0.87 | KMT2A (0.54) | KMT2AMEN1F10F2NOD2 | |
| SCHEMBL8694830 | 0.87 | MEN1 (0.69) | KMT2AMEN1F10F2NOD2 | |
| SCHEMBL10629278 | 0.86 | KMT2A (0.71) | KMT2AMEN1F10NOD2NOD1 | |
| SCHEMBL2476665 | 0.83 | CCR2 (0.60) | KMT2AMEN1CCR2KDM4ESMN1; SMN2 | |
| SCHEMBL25893621 | 0.82 | F10 (0.57) | KMT2AMEN1F10F2NOD2 | |
| Hydrochloric Acid SCHEMBL9085791 | 0.82 | ALDH1A1 (0.59) | KMT2AMEN1CCR2KDM4ESMN1; SMN2 | |
| SCHEMBL7681737 | 0.81 | KDM4E (0.42) | KMT2AMEN1F10F2NOD2 | |
| SCHEMBL7087440 | 0.79 | KDM4E (0.55) | KMT2AMEN1F10CCR2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6380230-B1 | FOR THERAPY OF DYSKINESIA, OBESITY, IRRITABLE BOWEL SYNDROME, DISEASES WHOSE TREATMENT REQUIRES STIMULATION OF THE CHOLECYSTOKININ CCK-A RECEPTORS | SANOFI-SYNTHELABO (FR) | 2002-04-30 | — | — | US | disclosed |
| CN-1276790-A | Carboxamidothiazole derivs., preparation, pharmaceutical composition contg. them | SANOFI SA (FR) | 2000-12-13 | — | — | CN | disclosed |