Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27413978 | 0.83 | MEN1 (0.31) | — | |
| SCHEMBL7676250 | 0.83 | HRH4 (0.31) | HRH4 | |
| SCHEMBL7682046 | 0.80 | POLB (0.37) | — | |
| SCHEMBL7673152 | 0.79 | CYP11B2 (0.38) | — | |
| SCHEMBL7676202 | 0.76 | PTGES (0.33) | HRH4 | |
| SCHEMBL7676533 | 0.74 | HRH4 (0.36) | HRH4 | |
| SCHEMBL7681996 | 0.73 | TLR8 (0.36) | HRH4 | |
| SCHEMBL7473964 | 0.73 | HRH4 (0.39) | HRH4 | |
| SCHEMBL7674269 | 0.72 | CGAS (0.36) | — | |
| SCHEMBL7682619 | 0.72 | TLR8 (0.38) | HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376490-B1 | STRONG N-METHYL-D-ASPARATE RECEPTOR ANTAGONISTS; USEFUL IN TREATING STROKES, ISCHEMIA, AND CENTRAL NERVOUS SYSTEM INJURIES | PFIZER INC | 2002-04-23 | — | — | US | disclosed |
| EP-0885212-B1 | QUINOXALINEDIONES | PFIZER RES AND BR DEV COMPANY (IE) | 2001-11-14 | — | — | EP | disclosed |
| EP-0885212-A1 | QUINOXALINEDIONES | Pfizer Research and Development Company, N.V./S.A. (IE) | 1998-12-23 | — | — | EP | disclosed |
| WO-1997032873-A1 | QUINOXALINEDIONES | PFIZER RESEARCH AND DEVELOPMENT COMPANY, N.V./S.A. (IE) | 1997-09-12 | — | — | WO | disclosed |