SCHEMBL8080533

SCHEMBL8080533

CC(C)(C)Oc1ccccc1CC(=O)O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CXCL8 P10145 4/20 0.58
CHRM1 P11229 1/20 0.51
AKR1B1 P15121 2/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
CAMK2A Q9UQM7 2/20 0.47
FABP4 P15090 1/20 0.47
FABP5 Q01469 1/20 0.47
TDP1 Q9NUW8 1/20 0.44
NR1H4 Q96RI1 2/20 0.43
MMP2 P08253 2/20 0.43
MMP8 P22894 2/20 0.43
MMP12 P39900 2/20 0.43
MMP13 P45452 2/20 0.43
MMP14 P50281 2/20 0.43
MMP16 P51512 2/20 0.43
CFD P00746 1/20 0.43
PLG P00747 1/20 0.43
PLAU P00749 1/20 0.43
F11 P03951 1/20 0.43
KLKB1 P03952 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5795204 0.86 KDM4E (0.55) CXCL8CHRM1AKR1B1L3MBTL1CAMK2A
SCHEMBL5319243 0.86 L3MBTL1 (0.58) CXCL8CHRM1L3MBTL1TTR
SCHEMBL21455218 0.83 CXCL8 (0.49) CXCL8CHRM1AKR1B1L3MBTL1CAMK2A
SCHEMBL8649516 0.83 CXCL8 (0.51) CXCL8CHRM1AKR1B1L3MBTL1CAMK2A
SCHEMBL534254 0.82 CXCL8 (0.58) CXCL8CHRM1AKR1B1L3MBTL1CAMK2A
SCHEMBL29782307 0.82 CXCL8 (0.58) CXCL8CHRM1AKR1B1L3MBTL1CAMK2A
Hydrochloric Acid SCHEMBL2530814 0.81 CXCL8 (0.57) CXCL8CHRM1AKR1B1L3MBTL1CAMK2A
SCHEMBL24200238 0.80 TBXAS1 (0.49) L3MBTL1
SCHEMBL6081047 0.80 FBP1 (0.52) CXCL8CHRM1AKR1B1L3MBTL1MMP8
SCHEMBL21455730 0.80 CXCL8 (0.49) CXCL8CHRM1AKR1B1L3MBTL1CAMK2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0758013-B1 Liquid crystalline optical film, compensating film for liquid crystal display and liquid crystal display NIPPON OIL CO LTD (JP) 2000-10-11 EP disclosed
US-5855971-A Liquid crystalline optical film, compensating film for liquid crystal display comprising the liquid crystalline optical film, and liquid crystal display having the compensating film NIPPON OIL COMPANY, LIMITED (JP) 1999-01-05 US disclosed
EP-0758013-A1 Liquid crystalline optical film, compensating film for liquid crystal display and liquid crystal display NIPPON OIL COMPANY, LIMITED (JP) 1997-02-12 EP disclosed