Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.34 |
| ▸ | CDK2 | P24941 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7675185 | 0.83 | CA12 (0.42) | ALDH1A1MAPTPOLBRAB9ALMNA | |
| SCHEMBL7683202 | 0.78 | ALDH1A1 (0.57) | GAAALDH1A1MAPTSMN1; SMN2RAB9A | |
| SCHEMBL7681327 | 0.77 | EPHX1 (0.58) | GAAALDH1A1MAPTSMN1; SMN2RAB9A | |
| SCHEMBL7677603 | 0.74 | ALDH1A1 (0.42) | GAAALDH1A1MAPTPOLBSMN1; SMN2 | |
| SCHEMBL7683185 | 0.72 | ALDH1A1 (0.41) | GAAALDH1A1MAPTPOLBSMN1; SMN2 | |
| SCHEMBL7679306 | 0.72 | ALDH1A1 (0.40) | GAAALDH1A1MAPTPOLBSMN1; SMN2 | |
| SCHEMBL7676323 | 0.72 | PDE4A (0.39) | ALDH1A1MAPTPOLBSMN1; SMN2RAB9A | |
| SCHEMBL7684169 | 0.71 | ALDH1A1 (0.37) | GAAALDH1A1POLBSMN1; SMN2RAB9A | |
| SCHEMBL6735881 | 0.70 | POLB (0.38) | GAAALDH1A1POLBSMN1; SMN2RAB9A | |
| SCHEMBL7680123 | 0.68 | THRB (0.38) | GAAALDH1A1MAPTPOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6472349-B1 | Pyridine-2,3-dicarboxylic acid diamides | BASF AKTIENGESELLSCHAFT (DE) | 2002-10-29 | — | — | US | disclosed |