Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.35 |
| ▸ | CDK2 | P24941 | 2/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7679294 | 0.92 | ALDH1A1 (0.34) | ALDH1A1POLBHPGDCCNE1CDK2 | |
| SCHEMBL7680208 | 0.92 | PDE4A (0.38) | ALDH1A1POLBHPGDCCNE1CDK2 | |
| SCHEMBL7683047 | 0.92 | PDE4A (0.38) | ALDH1A1POLBHPGDCCNE1CDK2 | |
| SCHEMBL7677586 | 0.86 | HTT (0.41) | ALDH1A1HPGDPDE4APDE4BPDE4C | |
| SCHEMBL7682616 | 0.86 | ALDH1A1 (0.39) | ALDH1A1POLBHPGDKDM4ETSHR | |
| SCHEMBL7677603 | 0.85 | ALDH1A1 (0.42) | ALDH1A1POLBHPGDGAAKMT2A | |
| SCHEMBL7679461 | 0.84 | CNR1 (0.39) | KMT2AMEN1 | |
| SCHEMBL7675233 | 0.83 | ALDH1A1 (0.34) | ALDH1A1POLBHPGDCCNE1CDK2 | |
| SCHEMBL7683507 | 0.83 | PDE4B (0.38) | ALDH1A1POLBHPGDCCNE1CDK2 | |
| SCHEMBL7685558 | 0.82 | PTGS2 (0.42) | ALDH1A1PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6472349-B1 | Pyridine-2,3-dicarboxylic acid diamides | BASF AKTIENGESELLSCHAFT (DE) | 2002-10-29 | — | — | US | claimed |