Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | SORT1 | Q99523 | 6/20 | 0.40 |
| ▸ | GRM5 | P41594 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ACLY | P53396 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SCD | O00767 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7683215 | 0.83 | GAA (0.40) | NPC1RAB9AALDH1A1TDP1LMNA | |
| SCHEMBL9214998 | 0.75 | KDM4E (0.53) | CA12CA2CA9SORT1NPC1 | |
| SCHEMBL7675174 | 0.74 | ALDH1A1 (0.46) | CA12CA2CA9SORT1GRM5 | |
| SCHEMBL262422 | 0.71 | GABRP (0.47) | SORT1KDM4EALDH1A1TDP1ACLY | |
| SCHEMBL29625359 | 0.71 | GABRP (0.47) | SORT1KDM4EALDH1A1TDP1ACLY | |
| SCHEMBL9216226 | 0.70 | KDM4E (0.46) | SORT1GRM5KDM4EALDH1A1ACLY | |
| SCHEMBL28545196 | 0.69 | GABRP (0.46) | SORT1KDM4EALDH1A1TDP1ACLY | |
| SCHEMBL6739536 | 0.68 | SORT1 (0.40) | CA12CA2CA9SORT1GRM5 | |
| SCHEMBL6573965 | 0.68 | GABRP (0.44) | SORT1KDM4EALDH1A1TDP1ACLY | |
| SCHEMBL30775057 | 0.67 | NPSR1 (0.47) | SORT1NPC1RAB9AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6472349-B1 | Pyridine-2,3-dicarboxylic acid diamides | BASF AKTIENGESELLSCHAFT (DE) | 2002-10-29 | — | — | US | disclosed |