Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.50 |
| ▸ | CA2 | P00918 | 4/20 | 0.50 |
| ▸ | CA9 | Q16790 | 4/20 | 0.50 |
| ▸ | CA4 | P22748 | 3/20 | 0.50 |
| ▸ | MMP2 | P08253 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | CTSG | P08311 | 1/20 | 0.41 |
| ▸ | CMA1 | P23946 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.41 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7685271 | 0.82 | MAP1LC3B (0.46) | CA1CA2CA9CA4NPSR1 | |
| Hydrochloric Acid SCHEMBL7687767 | 0.78 | CA1 (0.37) | CA1CA2CA9CA4MMP2 | |
| Hydrochloric Acid SCHEMBL7687768 | 0.78 | CA1 (0.37) | CA1CA2CA9CA4MMP2 | |
| SCHEMBL3213248 | 0.74 | MMP2 (0.46) | CA1CA2CA9CA4MMP2 | |
| SCHEMBL7686928 | 0.73 | MAP1LC3B (0.50) | CA1CA2CA9CA4HPGD | |
| SCHEMBL24282440 | 0.70 | PARL (0.50) | MMP2PKMCTSGCMA1HPGD | |
| SCHEMBL25979808 | 0.69 | L3MBTL1 (0.47) | CA1CA2MMP2PKMCTSG | |
| Hydrochloric Acid SCHEMBL27527583 | 0.68 | CA1 (0.35) | CA1CA2CA9CA4PKM | |
| SCHEMBL15164810 | 0.68 | MMP2 (0.43) | CA1CA2MMP2PKMGAA | |
| SCHEMBL5208476 | 0.68 | SMN1; SMN2 (0.76) | NPSR1SMN1; SMN2PKMGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6350749-B1 | SODIUM CHANNEL MODULATORS, ANTIARRHYTHMIA AND HYPOTENSIVE AGENTS; CARDIOVASCULAR DISORDERS, ANGINA PECTORIS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-02-26 | — | — | US | disclosed |
| EP-1057812-A1 | AMINOGUANIDINE HYDRAZONE DERIVATIVES, PROCESS FOR PRODUCING THE SAME AND DRUGS THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2000-12-06 | — | — | EP | disclosed |