Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KIF11 | P52732 | 13/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.45 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7847564 | 0.91 | SIRT1 (0.47) | DHODHMAPTKIF11SIRT1ABCG2 | |
| SCHEMBL7853413 | 0.90 | MAPT (0.55) | DHODHMAPTKIF11SIRT1 | |
| SCHEMBL7683286 | 0.88 | DHODH (0.49) | DHODHMAPTKIF11SIRT1MAPK1 | |
| SCHEMBL7843919 | 0.88 | ABCG2 (0.55) | KIF11SIRT1ABCG2ABCB1 | |
| SCHEMBL7855972 | 0.86 | SIRT1 (0.44) | DHODHMAPTKIF11SIRT1 | |
| SCHEMBL7855327 | 0.85 | KIF11 (0.47) | MAPTKIF11SIRT1ABCG2ABCB1 | |
| SCHEMBL7851311 | 0.85 | SIRT1 (0.46) | DHODHMAPTKIF11SIRT1MAPK1 | |
| SCHEMBL7854615 | 0.85 | KIF11 (0.52) | KIF11SIRT1ABCG2ABCB1 | |
| SCHEMBL7855042 | 0.84 | ABCG2 (0.45) | MAPTKIF11SIRT1ABCG2ABCB1 | |
| SCHEMBL7855705 | 0.83 | SIRT1 (0.45) | MAPTKIF11SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1070716-A1 | Beta-carboline derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2001-01-24 | — | — | EP | disclosed |