Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 18/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 18/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 18/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7665732 | 0.92 | ADRA1D (0.46) | ADRA1DADRA1AADRA1BTSHR | |
| SCHEMBL7668994 | 0.90 | ADRA1D (0.41) | ADRA1DADRA1AADRA1BTSHR | |
| SCHEMBL7660469 | 0.78 | ADRA1A (0.55) | ADRA1DADRA1AADRA1BTSHR | |
| SCHEMBL7683294 | 0.72 | ADRA1D (0.44) | ADRA1DADRA1AADRA1B | |
| SCHEMBL7662361 | 0.68 | ADRA1A (0.58) | ADRA1DADRA1AADRA1BTSHR | |
| SCHEMBL7658023 | 0.67 | ADRA1A (0.53) | ADRA1DADRA1AADRA1BTSHR | |
| SCHEMBL7664087 | 0.67 | ADRA1A (0.53) | ADRA1DADRA1AADRA1BTSHR | |
| SCHEMBL7660010 | 0.67 | ADRA1A (0.53) | ADRA1DADRA1AADRA1BTSHR | |
| SCHEMBL7665729 | 0.64 | ADRA1D (0.47) | ADRA1DADRA1AADRA1B | |
| SCHEMBL7662035 | 0.63 | ADRA1D (0.42) | ADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6339090-B1 | FOR THERAPY OF BENIGN PROSTATIC HYPERPLASIA | MERCK & CO., INC. | 2002-01-15 | — | — | US | disclosed |
| WO-2000006565-A1 | ALPHA 1a ADRENERGIC RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 2000-02-10 | — | — | WO | disclosed |