Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 7/20 | 0.46 |
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7678583 | 0.81 | ACHE (0.46) | ACHERAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL7684794 | 0.81 | ACHE (0.46) | ACHEALDH1A1TSHRPOLBMAPT | |
| SCHEMBL7924360 | 0.80 | ACHE (0.41) | ACHERAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL28135441 | 0.79 | NPC1 (0.48) | ACHERAB9ANPC1SMN1; SMN2ALDH1A1 | |
| Methylamine SCHEMBL10475930 | 0.73 | ALDH1A1 (0.47) | RAB9ANPC1SMN1; SMN2ALDH1A1CYP3A4 | |
| Dimethylamine SCHEMBL4362336 | 0.73 | ACHE (0.81) | ACHERAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL1485899 | 0.73 | ALDH1A1 (0.53) | RAB9ANPC1SMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL3036481 | 0.73 | ALDH1A1 (0.53) | RAB9ANPC1SMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL8918 | 0.73 | — | — | |
| SCHEMBL13166298 | 0.73 | ALDH1A1 (0.53) | RAB9ANPC1SMN1; SMN2ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6413947-B1 | Anilide derivative, production and use thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-07-02 | — | — | US | disclosed |
| EP-1040103-A1 | ANILIDE DERIVATIVE, PRODUCTION AND USE THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2000-10-04 | — | — | EP | disclosed |
| WO-1999032468-A1 | ANILIDE DERIVATIVE, PRODUCTION AND USE THEREOF | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-07-01 | — | — | WO | disclosed |