Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.31 |
| ▸ | GHSR | Q92847 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | ACE | P12821 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | CASP3 | P42574 | 1/20 | 0.30 |
| ▸ | CASP7 | P55210 | 1/20 | 0.30 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8176683 | 0.90 | TP53 (0.36) | TP53MEN1KMT2ACASP1CASP3 | |
| Hydrochloric Acid SCHEMBL7689556 | 0.89 | TP53 (0.36) | TP53MEN1KMT2ACASP1CASP3 | |
| SCHEMBL7685546 | 0.82 | CASP3 (0.38) | TP53MEN1KMT2ACASP1CASP3 | |
| SCHEMBL7684199 | 0.82 | TP53 (0.34) | TP53MEN1KMT2ACASP1CASP3 | |
| SCHEMBL8165549 | 0.79 | CASP1 (0.44) | CASP1CASP3 | |
| Hydrochloric Acid SCHEMBL7695543 | 0.78 | CASP3 (0.44) | CASP1CASP3 | |
| SCHEMBL7686947 | 0.76 | TP53 (0.37) | TP53MEN1KMT2ACASP1CASP3 | |
| SCHEMBL8171557 | 0.76 | ALDH1A1 (0.35) | TP53KMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7680236 | 0.75 | TP53 (0.33) | TP53MEN1KMT2ACASP1CASP3 | |
| Hydrochloric Acid SCHEMBL8176793 | 0.75 | UBE2M (0.35) | TP53KMT2ACYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376484-B1 | FOR PREVENTION AND/OR TREATMENT OF VARIOUS KINDS OF INFLAMMATORY DISEASE | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-04-23 | — | — | US | disclosed |