Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.40 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8065593 | 0.85 | ESRRG (0.45) | ALDH1A1KDM4ESMN1; SMN2PTGS1LMNA | |
| SCHEMBL8048418 | 0.83 | CACNA1H (0.37) | ANO1 | |
| SCHEMBL8048361 | 0.83 | POLB (0.36) | KDM4EMEN1KMT2AHDAC1ANO1 | |
| SCHEMBL8060073 | 0.82 | ESR1 (0.40) | ALDH1A1SMN1; SMN2NPSR1LMNAMEN1 | |
| SCHEMBL7686305 | 0.80 | ALDH1A1 (0.58) | ALDH1A1KDM4ESMN1; SMN2LMNAMEN1 | |
| SCHEMBL7527475 | 0.80 | HSD11B1 (0.38) | ALDH1A1KDM4ENPSR1ADRB2ADRB1 | |
| SCHEMBL8048655 | 0.80 | HTT (0.33) | ALDH1A1SMN1; SMN2NPSR1LMNAANO1 | |
| SCHEMBL8063598 | 0.79 | ANO1 (0.34) | ANO1HTT | |
| SCHEMBL8048369 | 0.78 | HDAC1 (0.46) | HDAC1ANO1NPC1HTTRAB9A | |
| SCHEMBL8063596 | 0.78 | HTT (0.32) | HDAC1ANO1HTTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1136451-C | Use of certain amides as probes for detection of antitubulin activity and resistance monitoring | ��ũҵ��ѧ��˾ | 2004-01-28 | — | — | CN | disclosed |
| US-6500405-B1 | EVALUATING THE SENSITIVITY OF A TEST CELL POPULATION TO AN ANTITUBULIN COMPOUND COMPRISING INCUBATING CELLS OR CELL EXTRACTS WITH AN AMIDE PROBE IN THE PRESENCE AND ABSENCE OF AN ANTITUBULIN TEST COMPOUND | DOW AGROSCIENCES LLC | 2002-12-31 | — | — | US | disclosed |
| US-6140362-A | INHIBITING MAMMALIAN CELL GROWTH IN BENIGN OR MALIGNANT TUMORS COMPRISING TREATING SAID CELLS WITH AN EFFECTIVE AMOUNT OF A N-ACETONYLARYLAMIDES COMPOUND | ROHM AND HAAS COMPANY (US) | 2000-10-31 | — | — | US | disclosed |
| EP-0843018-B1 | Use of certain amides as probes for detection of antitubulin activity and resistance monitoring | ROHM & HAAS (US) | 2000-07-05 | — | — | EP | disclosed |
| EP-0816331-B1 | Fungicidally active n-acetonylbenzamide compounds | ROHM & HAAS (US) | 2000-05-24 | — | — | EP | disclosed |
| US-5929098-A | Fungicidically active N-acetonylbenzamide compounds | ROHM AND HAAS COMPANY (US) | 1999-07-27 | — | — | US | disclosed |
| CN-1211736-A | Use of certain amides as probes for detection of antitubulin activity and resistance monitoring | ROHM & HAAS (US) | 1999-03-24 | — | — | CN | disclosed |
| EP-0843018-A1 | Use of certain amides as probes for detection of antitubulin activity and resistance monitoring | ROHM AND HAAS COMPANY (US) | 1998-05-20 | — | — | EP | disclosed |
| EP-0834311-A1 | Method for inhibiting the growth of mammalian cells | ROHM AND HAAS COMPANY (US) | 1998-04-08 | — | — | EP | disclosed |
| EP-0816331-A1 | Fungicidally active n-acetonylbenzamide compounds | ROHM AND HAAS COMPANY (US) | 1998-01-07 | — | — | EP | disclosed |