Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRG | P62508 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.44 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.41 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL287961 | 0.87 | ALDH1A1 (0.49) | LMNAALDH1A1MAPTPOLBMEN1 | |
| SCHEMBL7684116 | 0.85 | ALDH1A1 (0.50) | LMNAALDH1A1KDM4EMAPTPOLB | |
| SCHEMBL4186853 | 0.83 | HDAC8 (0.38) | LMNAALDH1A1KDM4EMAPTPOLB | |
| SCHEMBL8060073 | 0.82 | ESR1 (0.40) | ESRRGLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL8058869 | 0.82 | MAPT (0.59) | ESRRGLMNAALDH1A1TSHRKDM4E | |
| SCHEMBL8048361 | 0.81 | POLB (0.36) | CYP2C19KDM4EPOLBMEN1KMT2A | |
| SCHEMBL8048418 | 0.81 | CACNA1H (0.37) | — | |
| SCHEMBL8048504 | 0.81 | HDAC3 (0.53) | LMNAALDH1A1MAPTPOLBMEN1 | |
| SCHEMBL7527475 | 0.80 | HSD11B1 (0.38) | LMNAALDH1A1TSHRCYP2C19EPHX2 | |
| SCHEMBL8048655 | 0.80 | HTT (0.33) | ESRRGLMNAALDH1A1CYP2C19POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-10095756-A | — | — | None | — | — | JP | disclosed |
| EP-0816331-B1 | Fungicidally active n-acetonylbenzamide compounds | ROHM & HAAS (US) | 2000-05-24 | — | — | EP | disclosed |
| US-5929098-A | Fungicidically active N-acetonylbenzamide compounds | ROHM AND HAAS COMPANY (US) | 1999-07-27 | — | — | US | disclosed |
| JP-H1095756-A | N-ACETONYL BENZAMIDE COMPOUND HAVING ANTIMICROBIAL ACTIVITY | ROHM & HAAS CO | 1998-04-14 | — | — | JP | disclosed |
| EP-0816331-A1 | Fungicidally active n-acetonylbenzamide compounds | ROHM AND HAAS COMPANY (US) | 1998-01-07 | — | — | EP | disclosed |