SCHEMBL7679294

SCHEMBL7679294

CCCNC(=O)c1nc(C)ccc1C(=O)Nc1c(C)ccc(Br)c1C(=O)OC

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.34
POLB P06746 3/20 0.34
HPGD P15428 3/20 0.34
L3MBTL1 Q9Y468 4/20 0.33
CCNE1 P24864 2/20 0.33
CDK2 P24941 2/20 0.33
THRB P10828 1/20 0.33
RECQL P46063 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
KMT2A Q03164 3/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
F2 P00734 1/20 0.33
MAPT P10636 1/20 0.33
HTR1A P08908 1/20 0.33
SCN1A P35498 1/20 0.33
SCN2A Q99250 1/20 0.33
SCN3A Q9NY46 1/20 0.33
PDE4A P27815 1/20 0.32
PDE4B Q07343 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7682616 0.94 ALDH1A1 (0.39) ALDH1A1POLBHPGDL3MBTL1TDP1
SCHEMBL7684169 0.92 ALDH1A1 (0.37) ALDH1A1POLBHPGDL3MBTL1CCNE1
SCHEMBL7675233 0.91 ALDH1A1 (0.34) ALDH1A1POLBHPGDL3MBTL1CCNE1
SCHEMBL7686030 0.89 PTGS2 (0.35) ALDH1A1HPGDL3MBTL1KMT2AF2
SCHEMBL7683047 0.88 PDE4A (0.38) ALDH1A1POLBHPGDL3MBTL1CCNE1
SCHEMBL7685639 0.87 ALDH1A1 (0.36) ALDH1A1POLBHPGDL3MBTL1KMT2A
SCHEMBL7678756 0.85 HTT (0.38) ALDH1A1POLBHPGDL3MBTL1TDP1
SCHEMBL7675254 0.85 POLB (0.39) POLBKMT2ACYP3A4MEN1
SCHEMBL7685116 0.85 ALDH1A1 (0.34) ALDH1A1POLBHPGDL3MBTL1CCNE1
SCHEMBL7685879 0.85 MAPT (0.34) ALDH1A1POLBHPGDL3MBTL1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6472349-B1 Pyridine-2,3-dicarboxylic acid diamides BASF AKTIENGESELLSCHAFT (DE) 2002-10-29 US claimed