Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 11/20 | 0.49 |
| ▸ | PNP | P00491 | 3/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7565171 | 0.82 | HPRT1 (0.47) | HPRT1 | |
| Leteprinim SCHEMBL358491 | 0.82 | HPRT1 (0.50) | HPRT1PNP | |
| Leteprinim SCHEMBL6935182 | 0.81 | HPRT1 (0.49) | HPRT1PNP | |
| Leteprinim SCHEMBL6931317 | 0.81 | HPRT1 (0.49) | HPRT1PNP | |
| Leteprinim SCHEMBL194355 | 0.81 | HPRT1 (0.49) | HPRT1PNP | |
| SCHEMBL8629196 | 0.80 | HPRT1 (0.50) | HPRT1PNP | |
| Leteprinim SCHEMBL28734167 | 0.79 | HPRT1 (0.47) | HPRT1PNP | |
| SCHEMBL7397072 | 0.78 | HPRT1 (0.59) | HPRT1PNP | |
| SCHEMBL7374581 | 0.78 | HPRT1 (0.64) | HPRT1PNP | |
| SCHEMBL7391120 | 0.76 | HPRT1 (0.47) | HPRT1PNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001036419-A9 | USE OF 9-SUBSTITUTED HYPOXANTHINE DERIVATIVES TO STIMULATE REGENERATION OF NERVOUS TISSUE | NEOTHERAPEUTICS INC (US) | 2002-08-08 | — | — | WO | disclosed |