Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 2/20 | 0.53 |
| ▸ | DAO | P14920 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CCR2 | P41597 | 4/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | PHGDH | O43175 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | LDHA | P00338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6701629 | 0.86 | MCL1 (0.50) | MCL1DAOALDH1A1TSHRCCR2 | |
| SCHEMBL7682416 | 0.83 | F10 (0.44) | ALDH1A1CCR2CNR2POLBKMT2A | |
| SCHEMBL19362902 | 0.82 | KMT2A (0.46) | MCL1ALDH1A1TSHRCNR2CYP1A2 | |
| SCHEMBL5823619 | 0.82 | MCL1 (0.62) | MCL1DAOALDH1A1TSHRCCR2 | |
| SCHEMBL5806538 | 0.79 | MCL1 (0.58) | MCL1DAOALDH1A1TSHRCCR2 | |
| SCHEMBL8690109 | 0.77 | MCL1 (0.55) | MCL1DAOALDH1A1TSHRCCR2 | |
| SCHEMBL7881984 | 0.75 | ALDH1A1 (0.50) | MCL1DAOALDH1A1TSHRCNR2 | |
| SCHEMBL20562276 | 0.73 | POLB (0.44) | TSHRCNR2POLBKMT2AMEN1 | |
| SCHEMBL30912791 | 0.73 | POLB (0.44) | TSHRCNR2POLBKMT2AMEN1 | |
| SCHEMBL30885684 | 0.73 | POLB (0.44) | TSHRCNR2POLBKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6380230-B1 | FOR THERAPY OF DYSKINESIA, OBESITY, IRRITABLE BOWEL SYNDROME, DISEASES WHOSE TREATMENT REQUIRES STIMULATION OF THE CHOLECYSTOKININ CCK-A RECEPTORS | SANOFI-SYNTHELABO (FR) | 2002-04-30 | — | — | US | disclosed |
| CN-1276790-A | Carboxamidothiazole derivs., preparation, pharmaceutical composition contg. them | SANOFI SA (FR) | 2000-12-13 | — | — | CN | disclosed |