Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.55 |
| ▸ | DAO | P14920 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CCR2 | P41597 | 5/20 | 0.47 |
| ▸ | PHGDH | O43175 | 1/20 | 0.42 |
| ▸ | LDHA | P00338 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5823619 | 0.84 | MCL1 (0.62) | MCL1DAOALDH1A1CYP1A2POLB | |
| SCHEMBL5806538 | 0.81 | MCL1 (0.58) | MCL1DAOALDH1A1CYP1A2POLB | |
| SCHEMBL10773079 | 0.77 | MCL1 (0.66) | MCL1DAOALDH1A1CYP1A2POLB | |
| SCHEMBL7684555 | 0.77 | MCL1 (0.53) | MCL1DAOALDH1A1CYP1A2POLB | |
| SCHEMBL6701629 | 0.74 | MCL1 (0.50) | MCL1DAOALDH1A1CYP1A2POLB | |
| SCHEMBL26967654 | 0.73 | MCL1 (0.55) | MCL1DAOALDH1A1CYP1A2POLB | |
| SCHEMBL1082814 | 0.73 | DAO (0.37) | MCL1DAOPOLB | |
| SCHEMBL117186 | 0.72 | MCL1 (1.00) | MCL1DAOALDH1A1CYP1A2POLB | |
| SCHEMBL6754300 | 0.72 | HTR4 (0.49) | MCL1DAOALDH1A1CYP1A2POLB | |
| SCHEMBL20515860 | 0.71 | CCR2 (0.63) | MCL1DAOALDH1A1CYP1A2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5760032-A | GASTROINTESTINAL DISORDERS AND NERVOUS SYSTEM DISORDERS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1998-06-02 | — | — | US | disclosed |
| EP-0776892-A1 | THIENYLAZOLE COMPOUND AND THIENOTRIAZOLODIAZEPINE COMPOUND | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-06-04 | — | — | EP | disclosed |