Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | DAO | P14920 | 1/20 | 0.48 |
| ▸ | NOD2 | Q9HC29 | 6/20 | 0.46 |
| ▸ | NOD1 | Q9Y239 | 6/20 | 0.46 |
| ▸ | CCR2 | P41597 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7684555 | 0.86 | MCL1 (0.53) | MCL1MEN1KMT2ATSHRDAO | |
| SCHEMBL20037197 | 0.85 | MEN1 (0.45) | MEN1KMT2ATSHRNOD2NOD1 | |
| SCHEMBL7686006 | 0.82 | MCL1 (0.46) | MCL1MEN1KMT2ATSHRDAO | |
| SCHEMBL6702303 | 0.81 | TSHR (0.41) | MEN1KMT2ATSHRNOD2NOD1 | |
| SCHEMBL5823619 | 0.79 | MCL1 (0.62) | MCL1TSHRDAOCCR2ALDH1A1 | |
| SCHEMBL29463237 | 0.78 | NOD2 (0.57) | MEN1KMT2ATSHRNOD2NOD1 | |
| SCHEMBL5794123 | 0.78 | NOD2 (0.57) | MEN1KMT2ATSHRNOD2NOD1 | |
| SCHEMBL5806538 | 0.77 | MCL1 (0.58) | MCL1TSHRDAOCCR2ALDH1A1 | |
| SCHEMBL8690109 | 0.74 | MCL1 (0.55) | MCL1TSHRDAOCCR2ALDH1A1 | |
| SCHEMBL7256497 | 0.74 | MEN1 (0.63) | MCL1MEN1KMT2ATSHRNOD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040198793-A1 | Chemical process and new intermediates | SANOFI-SYNTHELABO (FR) | 2004-10-07 | — | — | US | disclosed |
| EP-1345897-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002044150-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2002-06-06 | — | — | WO | disclosed |