Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 3/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 5/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7685456 | 0.90 | TSHR (0.39) | TSHRHTTHSD17B10PDE4APDE4B | |
| SCHEMBL7683507 | 0.89 | PDE4B (0.38) | HTTHSD17B10PDE4APDE4BPDE4C | |
| SCHEMBL7685899 | 0.87 | ALDH1A1 (0.37) | TSHRHTTPDE4APDE4BPDE4C | |
| SCHEMBL7676322 | 0.87 | HTT (0.40) | TSHRHTTPDE4APDE4BPDE4C | |
| SCHEMBL7676352 | 0.86 | PTGS2 (0.37) | HTTPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7677391 | 0.85 | CNR1 (0.38) | PDE4APDE4BPDE4CPDE4DMEN1 | |
| SCHEMBL7682836 | 0.83 | KDM4E (0.39) | KDM4EHPGDMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7683047 | 0.80 | PDE4A (0.38) | HSD17B10PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7685639 | 0.79 | ALDH1A1 (0.36) | HTTHSD17B10PDE4APDE4BPDE4C | |
| SCHEMBL7684085 | 0.78 | PDE4D (0.40) | PDE4APDE4BPDE4CPDE4DHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6472349-B1 | Pyridine-2,3-dicarboxylic acid diamides | BASF AKTIENGESELLSCHAFT (DE) | 2002-10-29 | — | — | US | claimed |