Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7685456 | 0.88 | TSHR (0.39) | ALDH1A1KDM4ESMN1; SMN2KMT2AMEN1 | |
| SCHEMBL7685879 | 0.88 | MAPT (0.34) | ALDH1A1KDM4EKMT2AHPGDL3MBTL1 | |
| SCHEMBL7679294 | 0.87 | ALDH1A1 (0.34) | ALDH1A1KDM4ESMN1; SMN2KMT2AMEN1 | |
| SCHEMBL7676272 | 0.85 | ALDH1A1 (0.35) | ALDH1A1KDM4ESMN1; SMN2KMT2AMEN1 | |
| SCHEMBL7682616 | 0.85 | ALDH1A1 (0.39) | ALDH1A1KDM4ESMN1; SMN2TP53HPGD | |
| SCHEMBL7684146 | 0.85 | MAPT (0.35) | ALDH1A1KDM4ESMN1; SMN2KMT2AMEN1 | |
| SCHEMBL7686030 | 0.85 | PTGS2 (0.35) | ALDH1A1KDM4EKMT2AMEN1HPGD | |
| SCHEMBL7675254 | 0.85 | POLB (0.39) | KMT2AMEN1CYP2C9CNR2POLB | |
| SCHEMBL7679448 | 0.79 | SMN1; SMN2 (0.33) | ALDH1A1KDM4ESMN1; SMN2KMT2AMEN1 | |
| SCHEMBL7684725 | 0.79 | TSHR (0.38) | ALDH1A1KDM4ESMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6472349-B1 | Pyridine-2,3-dicarboxylic acid diamides | BASF AKTIENGESELLSCHAFT (DE) | 2002-10-29 | — | — | US | claimed |