Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 3/20 | 0.55 |
| ▸ | ACACA | Q13085 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | GPR139 | Q6DWJ6 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6253330 | 1.00 | ACACB (0.55) | ACACBACACAMEN1KMT2AATM | |
| SCHEMBL6254231 | 0.85 | ACACB (0.56) | ACACBACACAMEN1KMT2AL3MBTL1 | |
| SCHEMBL6252896 | 0.85 | ACACB (0.56) | ACACBACACAMEN1KMT2AL3MBTL1 | |
| SCHEMBL13683332 | 0.84 | ALDH1A1 (0.63) | ACACBACACAMEN1KMT2AL3MBTL1 | |
| SCHEMBL7714868 | 0.84 | ALDH1A1 (0.63) | ACACBACACAMEN1KMT2AL3MBTL1 | |
| SCHEMBL16714724 | 0.83 | TSHR (0.73) | MEN1KMT2AL3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL5016632 | 0.83 | TSHR (0.73) | MEN1KMT2AL3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL12384758 | 0.83 | ACACB (0.54) | ACACBACACAMEN1KMT2AL3MBTL1 | |
| SCHEMBL7897298 | 0.81 | SMN1; SMN2 (0.69) | MEN1KMT2AATML3MBTL1ALDH1A1 | |
| SCHEMBL8445815 | 0.81 | GPR139 (0.55) | ACACBACACAMEN1KMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6500986-B1 | RACEMIZATION OF OPTICALLY ACTIVE AMIDES; CONVERSION TO AMINES | BAYER AKTIENGESELLSCHAFT (DE) | 2002-12-31 | — | — | US | claimed |
| EP-0757981-B1 | Process for the preparation of racemic amino derivatives | BAYER AG (DE) | 2000-02-16 | — | — | EP | claimed |
| EP-0757981-A1 | Process for the preparation of racemic amino derivatives | BAYER AG (DE) | 1997-02-12 | — | — | EP | claimed |
| US-6500986-B1 | RACEMIZATION OF OPTICALLY ACTIVE AMIDES; CONVERSION TO AMINES | BAYER AKTIENGESELLSCHAFT (DE) | 2002-12-31 | — | — | US | disclosed |
| EP-0757981-B1 | Process for the preparation of racemic amino derivatives | BAYER AG (DE) | 2000-02-16 | — | — | EP | disclosed |
| US-5885787-A | Process for preparing optically active amines | BAYER AKTIEGESELLSCHAFT (DE) | 1999-03-23 | — | — | US | disclosed |
| EP-0757981-A1 | Process for the preparation of racemic amino derivatives | BAYER AG (DE) | 1997-02-12 | — | — | EP | disclosed |