SCHEMBL7685207

SCHEMBL7685207

COc1cc(-c2ncc([N+](=O)[O-])cc2Cl)ccc1Cl

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDGFRB P09619 1/20 0.45
PDGFRA P16234 1/20 0.45
DYRK1A Q13627 1/20 0.45
MAPT P10636 7/20 0.44
SMN1; SMN2 Q16637 4/20 0.44
HPGD P15428 3/20 0.44
RAB9A P51151 3/20 0.44
NPC1 O15118 2/20 0.44
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2D6 P10635 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
PSD A5PKW4 1/20 0.43
LMNA P02545 3/20 0.43
PKM P14618 2/20 0.42
KMO O15229 1/20 0.42
RIPK2 O43353 1/20 0.42
HSD17B10 Q99714 1/20 0.41
RORC P51449 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7684064 0.81 PSD (0.48) PDGFRBPDGFRADYRK1AMAPTSMN1; SMN2
SCHEMBL7604725 0.77 DYRK1A (0.56) PDGFRBPDGFRADYRK1ANPC1CYP3A4
SCHEMBL15391290 0.77 KMT2A (0.50) DYRK1AMAPTHPGDLMNAHSD17B10
SCHEMBL30675942 0.74 PDGFRB (0.44) PDGFRBPDGFRAMAPTSMN1; SMN2HPGD
SCHEMBL26927019 0.74 PDGFRB (0.44) PDGFRBPDGFRAMAPTSMN1; SMN2HPGD
SCHEMBL57125 0.74 HTT (0.68) MAPTSMN1; SMN2HPGDRAB9ANPC1
SCHEMBL17629945 0.74 VCAM1 (0.47) MAPTNPC1LMNAPKMHSD17B10
SCHEMBL14018586 0.74 MAPT (0.47) MAPTRAB9ANPC1LMNAHSD17B10
SCHEMBL6177440 0.74 ALDH1A1 (0.54) DYRK1AMAPTSMN1; SMN2HPGDRAB9A
SCHEMBL29739398 0.73 MAPT (0.51) PDGFRBPDGFRAMAPTHPGDLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0920415-A1 SUBSTITUTED 2-PHENYLPYRIDINE AS HERBICIDE BASF AKTIENGESELLSCHAFT (DE) 1999-06-09 EP claimed
WO-1998007700-A1 SUBSTITUTED 2-PHENYLPYRIDINE AS HERBICIDE BASF AKTIENGESELLSCHAFT (DE) 1998-02-26 WO claimed
US-6448205-B1 FOR THE DESICCATION AND/OR DEFOLIATION OF PLANTS BASF AKTIENGESELLSCHAFT (DE) 2002-09-10 US disclosed
EP-0920415-A1 SUBSTITUTED 2-PHENYLPYRIDINE AS HERBICIDE BASF AKTIENGESELLSCHAFT (DE) 1999-06-09 EP disclosed
WO-1998007700-A1 SUBSTITUTED 2-PHENYLPYRIDINE AS HERBICIDE BASF AKTIENGESELLSCHAFT (DE) 1998-02-26 WO disclosed