SCHEMBL7684064

SCHEMBL7684064

COc1cc(-c2ccc([N+](=O)[O-])cn2)ccc1Cl

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PSD A5PKW4 1/20 0.48
PDGFRB P09619 1/20 0.48
PDGFRA P16234 1/20 0.48
KMO O15229 1/20 0.48
MAPT P10636 6/20 0.47
KMT2A Q03164 5/20 0.47
RAB9A P51151 4/20 0.47
SMN1; SMN2 Q16637 3/20 0.47
MEN1 O00255 3/20 0.47
PKM P14618 1/20 0.45
DYRK1A Q13627 1/20 0.45
NPC1 O15118 3/20 0.44
HPGD P15428 2/20 0.44
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2D6 P10635 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
LMNA P02545 3/20 0.44
TDP1 Q9NUW8 3/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2068750 0.89 MAPT (0.58) PDGFRBPDGFRAMAPTKMT2ARAB9A
SCHEMBL5208906 0.83 PTGS2 (0.52) PDGFRBPDGFRAMAPTKMT2ARAB9A
SCHEMBL7685207 0.81 PDGFRB (0.45) PSDPDGFRBPDGFRAKMOMAPT
SCHEMBL24685670 0.79 MAPT (0.46) MAPTKMT2AMEN1HPGDCYP1A2
SCHEMBL14988198 0.79 NPC1 (0.59) MAPTKMT2ARAB9ASMN1; SMN2MEN1
SCHEMBL21290163 0.79 KMO (0.50) PDGFRBPDGFRAKMOMAPTKMT2A
SCHEMBL8204617 0.78 PDE4A (0.53) MAPTKMT2ARAB9ASMN1; SMN2MEN1
SCHEMBL57125 0.77 HTT (0.68) MAPTRAB9ASMN1; SMN2PKMNPC1
SCHEMBL16835850 0.77 KMT2A (0.59) PDGFRBPDGFRAMAPTKMT2ARAB9A
SCHEMBL7604435 0.77 DYRK1A (0.56) PDGFRBPDGFRAKMOKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0920415-A1 SUBSTITUTED 2-PHENYLPYRIDINE AS HERBICIDE BASF AKTIENGESELLSCHAFT (DE) 1999-06-09 EP claimed
WO-1998007700-A1 SUBSTITUTED 2-PHENYLPYRIDINE AS HERBICIDE BASF AKTIENGESELLSCHAFT (DE) 1998-02-26 WO claimed
US-6448205-B1 FOR THE DESICCATION AND/OR DEFOLIATION OF PLANTS BASF AKTIENGESELLSCHAFT (DE) 2002-09-10 US disclosed
EP-0920415-A1 SUBSTITUTED 2-PHENYLPYRIDINE AS HERBICIDE BASF AKTIENGESELLSCHAFT (DE) 1999-06-09 EP disclosed
WO-1998007700-A1 SUBSTITUTED 2-PHENYLPYRIDINE AS HERBICIDE BASF AKTIENGESELLSCHAFT (DE) 1998-02-26 WO disclosed