Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RHOC | P08134 | 2/20 | 0.51 |
| ▸ | RHOA | P61586 | 2/20 | 0.51 |
| ▸ | P2RX1 | P51575 | 4/20 | 0.45 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.42 |
| ▸ | ACP1 | P24666 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | XPO1 | O14980 | 1/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11168074 | 0.88 | MAPT (0.63) | RHOCRHOAP2RX1MAPTALDH1A1 | |
| SCHEMBL11117725 | 0.87 | RHOC (0.46) | RHOCRHOAP2RX1IDO1LMNA | |
| SCHEMBL7574473 | 0.87 | RIPK1 (0.49) | RHOCRHOAP2RX1LMNAMAPT | |
| SCHEMBL11116368 | 0.87 | KDM4E (0.44) | RHOCRHOAP2RX1IDO1LMNA | |
| SCHEMBL6231339 | 0.86 | TRPA1 (0.46) | RHOCRHOAP2RX1LMNAMAPT | |
| SCHEMBL3657741 | 0.82 | XPO1 (0.43) | RHOCRHOAP2RX1IDO1LMNA | |
| SCHEMBL1972751 | 0.82 | P2RX1 (0.46) | P2RX1IDO1LMNAMAPTRAPGEF4 | |
| SCHEMBL6231746 | 0.82 | TRPA1 (0.56) | P2RX1IDO1LMNAMAPTRAPGEF4 | |
| SCHEMBL12587250 | 0.80 | MAPT (0.47) | P2RX1IDO1LMNAMAPTRAPGEF4 | |
| SCHEMBL21851562 | 0.79 | P2RX1 (0.47) | P2RX1IDO1LMNAMAPTRAPGEF4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6335303-B1 | EFFECTIVE IN POLYMERIZATION OF ALPHA OLEFINS TO HIGH MOLECULAR WEIGHT POLYMERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2002-01-01 | — | — | US | disclosed |
| WO-1998045039-A1 | POLYMERIZATION CATALYSTS CONTAINING ELECTRON-WITHDRAWING AMIDE LIGANDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1998-10-15 | — | — | WO | disclosed |