Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 7/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | RHOC | P08134 | 2/20 | 0.42 |
| ▸ | RHOA | P61586 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ACP1 | P24666 | 1/20 | 0.40 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7574473 | 0.94 | RIPK1 (0.49) | TRPA1CYP1A2RIPK1RHOCRHOA | |
| SCHEMBL6231746 | 0.86 | TRPA1 (0.56) | TRPA1CYP1A2LMNAMAPTRAPGEF4 | |
| SCHEMBL7685789 | 0.86 | RHOC (0.51) | TRPA1CYP1A2RHOCRHOALMNA | |
| SCHEMBL14015102 | 0.84 | RAPGEF4 (0.45) | TRPA1CYP1A2RIPK1ADRA2ACNR2 | |
| SCHEMBL6235877 | 0.82 | LMNA (0.55) | ABL1LMNAMAPTRAPGEF4MEN1 | |
| SCHEMBL25590656 | 0.81 | LMNA (0.54) | ABL1LMNAMAPTRAPGEF4MEN1 | |
| SCHEMBL3400985 | 0.81 | ADRA2A (0.53) | ADRA2AABL1 | |
| SCHEMBL6236337 | 0.81 | MEN1 (0.55) | TRPA1ABL1RHOCRHOACNR2 | |
| SCHEMBL28868424 | 0.81 | TRPA1 (0.47) | TRPA1CYP1A2ABL1CNR2MAPT | |
| SCHEMBL4966922 | 0.79 | TRPA1 (0.53) | TRPA1CYP1A2LMNAMAPTRAPGEF4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1530562-A1 | OPTICALLY ACTIVE 1-(FLUORO-,TRIFLUOROMETHYL-OR TRIFLUOROMETHOXY-SUBSTITUTED PHENYL)ALKYLAMINE N-MONOALKYL DERIVATIVES AND PROCESS FOR PRODUCING SAME | Central Glass Company, Limited (JP) | 2005-05-18 | — | — | EP | disclosed |
| WO-2004022521-A1 | OPTICALLY ACTIVE 1-(FLUORO-,TRIFLUOROMETHYL-OR TRIFLUOROMETHOXY-SUBSTITUTED PHENYL)ALKYLAMINE N-MONOALKYL DERIVATIVES AND PROCESS FOR PRODUCING SAME | CENTRAL GLASS COMPANY, LIMITED (JP) | 2004-03-18 | — | — | WO | disclosed |