Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 2/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.42 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20654333 | 0.79 | NPC1 (0.59) | ALDH1A1ATML3MBTL1 | |
| SCHEMBL16127491 | 0.77 | IKBKB (0.53) | MAOBIDO1TDP1SCN2AHRH1 | |
| SCHEMBL29134978 | 0.76 | GRIN1 (0.55) | ALDH1A1GAAATMMAOBL3MBTL1 | |
| SCHEMBL26827704 | 0.75 | MAOB (0.62) | MAOBIDO1SCN2AKDM1AKIF11 | |
| SCHEMBL5318644 | 0.74 | ADORA2A (0.60) | ALDH1A1GAAATMMAOBL3MBTL1 | |
| SCHEMBL11483670 | 0.74 | ALDH1A1 (0.56) | ALDH1A1GAAATMMAOBL3MBTL1 | |
| SCHEMBL4389561 | 0.74 | NPC1 (0.58) | ALDH1A1GAAL3MBTL1 | |
| SCHEMBL13247949 | 0.73 | MAOB (0.57) | MAOBIDO1TDP1KDM1AKIF11 | |
| SCHEMBL40311 | 0.73 | TSHR (0.53) | ALDH1A1GAAATMMAOBIDO1 | |
| SCHEMBL16068085 | 0.73 | GRIN1 (0.55) | ALDH1A1GAAATMMAOBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002006243-A1 | TETRAHYDROPYRIMIDINES AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2002-01-24 | — | — | WO | disclosed |