Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.38 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.37 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.36 |
| ▸ | KIT | P10721 | 1/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6487652 | 0.94 | ALDH1A1 (0.43) | ALDH1A1TSHRMEN1KMT2APOLB | |
| SCHEMBL6477918 | 0.91 | LPAR1 (0.39) | ALDH1A1TSHRMEN1KMT2APOLB | |
| SCHEMBL7693571 | 0.88 | LPAR1 (0.39) | ALDH1A1MEN1KMT2APOLBMET | |
| SCHEMBL7692498 | 0.85 | LPAR1 (0.39) | ALDH1A1TSHRMEN1KMT2APOLB | |
| SCHEMBL7686564 | 0.84 | LPAR1 (0.43) | ALDH1A1POLBMETADRB1ADRB3 | |
| SCHEMBL7692913 | 0.83 | LPAR1 (0.39) | ALDH1A1MEN1KMT2APOLBMET | |
| SCHEMBL6488702 | 0.83 | LPAR1 (0.39) | ALDH1A1MEN1KMT2APOLBMET | |
| SCHEMBL7692473 | 0.83 | MET (0.38) | ALDH1A1MEN1KMT2APOLBMET | |
| SCHEMBL7686800 | 0.82 | ADRB1 (0.39) | ALDH1A1MEN1KMT2APOLBMAPK1 | |
| SCHEMBL7693432 | 0.82 | MET (0.39) | ALDH1A1MEN1KMT2AMETLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002000622-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-03 | — | — | WO | disclosed |