Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 20/20 | 0.80 |
| ▸ | MMP1 | P03956 | 19/20 | 0.80 |
| ▸ | MMP9 | P14780 | 19/20 | 0.80 |
| ▸ | ADAM17 | P78536 | 18/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7009051 | 0.89 | MMP13 (1.00) | MMP13MMP1MMP9ADAM17 | |
| SCHEMBL7008539 | 0.82 | MMP13 (0.77) | MMP13MMP1MMP9ADAM17 | |
| SCHEMBL7015811 | 0.82 | MMP13 (1.00) | MMP13MMP1MMP9ADAM17 | |
| SCHEMBL6290710 | 0.82 | MMP13 (0.78) | MMP13MMP1MMP9ADAM17 | |
| SCHEMBL7011999 | 0.81 | MMP1 (0.80) | MMP13MMP1MMP9ADAM17 | |
| SCHEMBL6293930 | 0.81 | MMP9 (0.80) | MMP13MMP1MMP9ADAM17 | |
| SCHEMBL7006979 | 0.81 | MMP13 (1.00) | MMP13MMP1MMP9ADAM17 | |
| SCHEMBL7539035 | 0.81 | MMP13 (0.81) | MMP13MMP1MMP9ADAM17 | |
| SCHEMBL6293982 | 0.80 | MMP9 (0.80) | MMP13MMP1MMP9ADAM17 | |
| SCHEMBL6289991 | 0.80 | MMP9 (0.80) | MMP13MMP1MMP9ADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6498167-B2 | NITROGEN CONTAINING BICYCLIC HETEROAROMATIC COMPOUND CONTAINING SULFONAMIDE AND HYDROXYAMIDE GROUPS, USEFUL IN TREATMENT OF ARTHRITIS, TUMOR METASTASIS, TISSUE ULCERATION, ABNORMAL WOUND HEALING, BONE DISEASE AND HIV INFECTIONS | AMERICAN CYANAMID COMPANY | 2002-12-24 | — | — | US | disclosed |
| US-20010025047-A1 | Preparation and use of ortho-sulfonamido bicyclic heteroaryl hydroxamic acids as matrix metalloproteinase and tace inhibitors | WYETH HOLDINGS CORPORATION | 2001-09-27 | — | — | US | disclosed |
| US-6228869-B1 | ANTITUMOR, ANTIMETASTASIS, ANTIARTHRITIC, AND WOUND HEALING AGENTS; QUINOLINE AND ISOQUINOLINE DERIVATIVES | AMERICAN CYANAMID COMPANY | 2001-05-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010025047-A1 | Preparation and use of ortho-sulfonamido bicyclic heteroaryl hydroxamic acids as matrix metalloproteinase and tace inhibitors | MSR1, TIMP3, TGFBR2 | MMP13 36/4885MMP1 40/4885MMP9 21/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.