Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 3/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7692937 | 0.82 | NCF1 (0.41) | KDM4ERECQLTDP1MAPK1LMNA | |
| SCHEMBL12299798 | 0.82 | ALDH1A1 (0.48) | KDM4ERECQLTDP1MAPK1APP | |
| SCHEMBL13413138 | 0.80 | KDM4E (0.42) | KDM4ERECQLTDP1MAOADYRK1A | |
| SCHEMBL13021583 | 0.80 | MEN1 (0.45) | KDM4ERECQLTDP1MAOADYRK1A | |
| SCHEMBL3475322 | 0.76 | ALDH1A1 (0.41) | KDM4ERECQLTDP1MAOADYRK1A | |
| SCHEMBL22219086 | 0.76 | ALDH1A1 (0.41) | KDM4ERECQLTDP1MAOADYRK1A | |
| SCHEMBL28826013 | 0.75 | LTA4H (0.39) | MAPK1LMNAHPGD | |
| SCHEMBL12703538 | 0.74 | KDM4E (0.61) | KDM4ERECQLTDP1MAPK1APP | |
| SCHEMBL3611926 | 0.74 | KDM4E (0.61) | KDM4ERECQLTDP1MAPK1APP | |
| SCHEMBL10757339 | 0.74 | ALDH1A1 (0.55) | KDM4ERECQLTDP1MAPK1APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023172667-A2 | SUBSTITUTED IMIDAZO[1,5-a]PYRIDINE N-HETEROCYCLIC CARBENE (NHC) LIGANDS, CATALYST COMPLEXES THEREOF, AND METHODS USING SAME | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2023-09-14 | — | — | WO | claimed |
| US-6337423-B1 | BIND TO VOLTAGE-GATED SODIUM ION CHANNELS TO MODULATE ACTIVITY | ADVANCED MEDICINE, INC. | 2002-01-08 | — | — | US | claimed |
| WO-2023172667-A2 | SUBSTITUTED IMIDAZO[1,5-a]PYRIDINE N-HETEROCYCLIC CARBENE (NHC) LIGANDS, CATALYST COMPLEXES THEREOF, AND METHODS USING SAME | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2023-09-14 | — | — | WO | disclosed |