Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | TEK | Q02763 | 1/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.36 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 5/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7692118 | 0.91 | AURKA (0.37) | AURKALCKMETKDRTEK | |
| SCHEMBL7688229 | 0.91 | MEN1 (0.35) | AURKALCKKDRTEKLPAR1 | |
| SCHEMBL7686590 | 0.90 | LMNA (0.34) | AURKALCKKDRTEKLPAR1 | |
| SCHEMBL7694610 | 0.87 | RPS6KB1 (0.41) | AURKALPAR1LPAR5ALDH1A1GAA | |
| SCHEMBL7693500 | 0.87 | ALDH1A1 (0.35) | AURKALPAR1LPAR5ALDH1A1HPGD | |
| SCHEMBL7692452 | 0.86 | ADRB1 (0.34) | AURKALCKKDRTEKMEN1 | |
| SCHEMBL7687663 | 0.86 | ALDH1A1 (0.37) | LPAR1LPAR5ALDH1A1GAAMEN1 | |
| SCHEMBL7692572 | 0.85 | ALDH1A1 (0.46) | AURKALCKMETKDRTEK | |
| SCHEMBL7692573 | 0.85 | ALDH1A1 (0.46) | AURKALCKMETKDRTEK | |
| SCHEMBL7694215 | 0.84 | POLB (0.38) | LPAR1LPAR5ALDH1A1GAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002000622-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-03 | — | — | WO | disclosed |