Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.34 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.34 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7686590 | 0.95 | LMNA (0.34) | MEN1KMT2ALMNAALDH1A1GAA | |
| SCHEMBL7692118 | 0.93 | AURKA (0.37) | MEN1KMT2ALMNAALDH1A1GAA | |
| SCHEMBL7687331 | 0.91 | AURKA (0.39) | MEN1KMT2ALMNAALDH1A1GAA | |
| SCHEMBL7692452 | 0.91 | ADRB1 (0.34) | MEN1KMT2ALMNAMAPK1MAPT | |
| SCHEMBL7705522 | 0.90 | ADRB3 (0.40) | LMNAALDH1A1ADRB1ADRB3HPGD | |
| SCHEMBL7694610 | 0.89 | RPS6KB1 (0.41) | MEN1KMT2ALMNAALDH1A1GAA | |
| SCHEMBL7693500 | 0.89 | ALDH1A1 (0.35) | MEN1KMT2ALMNAALDH1A1MAPK1 | |
| SCHEMBL7687663 | 0.88 | ALDH1A1 (0.37) | MEN1KMT2ALMNAALDH1A1GAA | |
| SCHEMBL7692587 | 0.86 | ADRB3 (0.38) | ALDH1A1GAAADRB1ADRB3HPGD | |
| SCHEMBL7692585 | 0.86 | ADRB3 (0.38) | ALDH1A1GAAADRB1ADRB3HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002000622-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-03 | — | — | WO | disclosed |