SCHEMBL768773

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1686235	0.89	TARBP2 (0.56)	TARBP2ALDH1A1MAPTSMN1; SMN2KDM4E
	SCHEMBL1686445	0.86	TARBP2 (0.54)	TARBP2ALDH1A1MAPTSMN1; SMN2KDM4E
	SCHEMBL1686239	0.86	TRPV1 (0.52)	TARBP2ALDH1A1MAPTSMN1; SMN2MAPK1
	SCHEMBL12000496	0.86	TARBP2 (0.52)	TARBP2ALDH1A1MAPTSMN1; SMN2MAPK1
	SCHEMBL2568755	0.84	PTGS1 (0.58)	ALDH1A1MAPTSMN1; SMN2MAPK1KDM4E
	SCHEMBL1226917	0.83	TARBP2 (0.50)	TARBP2ALDH1A1MAPTSMN1; SMN2MAPK1
	SCHEMBL31587044	0.83	ADORA3 (0.50)	TARBP2ALDH1A1MAPTSMN1; SMN2MAPK1
	SCHEMBL1753377	0.83	CYP1A2 (0.51)	TARBP2ALDH1A1MAPTSMN1; SMN2MAPK1
	SCHEMBL768777	0.83	PTGS1 (0.51)	TARBP2ALDH1A1MAPTSMN1; SMN2MAPK1
	SCHEMBL17079301	0.83	TARBP2 (0.50)	TARBP2ALDH1A1MAPTSMN1; SMN2MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.