SCHEMBL768777

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2565415	0.89	PTGS1 (0.52)	PTGS1PTPN1TARBP2ALDH1A1HPGD
	SCHEMBL16110874	0.88	PTGS1 (0.48)	PTGS1PTPN1TARBP2ALDH1A1HPGD
	SCHEMBL768605	0.86	PTGS1 (0.46)	PTGS1PTPN1TARBP2ALDH1A1HPGD
	SCHEMBL12000496	0.86	TARBP2 (0.52)	PTGS1PTPN1TARBP2ALDH1A1HPGD
	SCHEMBL31587044	0.83	ADORA3 (0.50)	PTGS1PTPN1TARBP2ALDH1A1HPGD
	SCHEMBL1226917	0.83	TARBP2 (0.50)	PTGS1PTPN1TARBP2ALDH1A1HPGD
	SCHEMBL768773	0.83	TARBP2 (0.50)	PTGS1PTPN1TARBP2ALDH1A1HPGD
	SCHEMBL17079301	0.83	TARBP2 (0.50)	PTGS1PTPN1TARBP2ALDH1A1HPGD
	SCHEMBL1753377	0.83	CYP1A2 (0.51)	PTPN1TARBP2ALDH1A1HPGDKDM4E
	SCHEMBL4031918	0.83	ALDH1A1 (0.65)	PTGS1ALDH1A1HPGDKDM4EGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.