Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ3 | O43525 | 3/20 | 0.36 |
| ▸ | KCNQ2 | O43526 | 3/20 | 0.36 |
| ▸ | KCNE1 | P15382 | 2/20 | 0.36 |
| ▸ | KCNQ1 | P51787 | 2/20 | 0.36 |
| ▸ | BACE1 | P56817 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.35 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KMO | O15229 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL875231 | 0.84 | HCAR2 (0.42) | BACE1DHODHBACE2S1PR1S1PR3 | |
| Hydrochloric Acid SCHEMBL7687784 | 0.82 | HCAR2 (0.41) | BACE1DHODHBACE2S1PR1S1PR3 | |
| SCHEMBL7910786 | 0.82 | BACE1 (0.39) | BACE1BACE2S1PR1S1PR3 | |
| SCHEMBL17480173 | 0.82 | BACE1 (0.38) | KCNQ3KCNQ2BACE1DHODHBACE2 | |
| SCHEMBL31514824 | 0.82 | DPP4 (0.39) | KCNQ3KCNQ2KCNE1KCNQ1BACE1 | |
| SCHEMBL257014 | 0.82 | DPP4 (0.39) | KCNQ3KCNQ2KCNE1KCNQ1BACE1 | |
| SCHEMBL3580724 | 0.79 | L3MBTL1 (0.43) | SMN1; SMN2NPC1ALDH1A1TSHRRAB9A | |
| SCHEMBL1661089 | 0.78 | DGAT1 (0.35) | BACE1NPC1ALDH1A1RAB9AHCAR2 | |
| SCHEMBL12780507 | 0.78 | BACE1 (0.36) | KCNQ3KCNQ2KCNE1KCNQ1BACE1 | |
| SCHEMBL31255330 | 0.78 | ALDH1A1 (0.44) | BACE1ALDH1A1BACE2S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117126163-A | Benzo heterocyclic compound, and preparation method and application thereof | 中以海德人工智能药物研发股份有限公司 | 2023-11-28 | — | — | CN | disclosed |
| EP-3036235-B1 | NEW BIS-AMIDO PYRIDINES | BOEHRINGER INGELHEIM INT (DE) | 2017-04-19 | — | — | EP | disclosed |
| EP-3036235-B1 | NEW BIS-AMIDO PYRIDINES | BOEHRINGER INGELHEIM INT (DE) | 2017-04-19 | — | — | EP | disclosed |
| US-9249151-B2 | Bis-amido pyridines | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2016-02-02 | — | — | US | disclosed |
| US-9249151-B2 | Bis-amido pyridines | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2016-02-02 | — | — | US | disclosed |
| US-9249151-B2 | Bis-amido pyridines | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2016-02-02 | — | — | US | disclosed |
| US-20150057286-A1 | NEW BIS-AMIDO PYRIDINES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-02-26 | — | — | US | disclosed |
| US-20150057286-A1 | NEW BIS-AMIDO PYRIDINES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-02-26 | — | — | US | disclosed |
| US-20150057286-A1 | NEW BIS-AMIDO PYRIDINES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-02-26 | — | — | US | disclosed |
| WO-2015025018-A1 | NEW BIS-AMIDO PYRIDINES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-02-26 | — | — | WO | disclosed |
| US-6274536-B1 | CROPS, AGRICULTURE; PRE- AND POSTEMERGENCE | SYNGENTA CROP PROTECTION, INC. | 2001-08-14 | — | — | US | disclosed |
| US-6204221-B1 | Herbicides | SYNGENTA CROP PROTECTION, INC. | 2001-03-20 | — | — | US | disclosed |
| EP-1080088-A1 | PYRIDYL-PYRAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND THEIR USE AS HERBICIDES | Novartis AG (CH) | 2001-03-07 | — | — | EP | disclosed |
| CN-1250446-A | Pyrazole derivatives as herbicides | NOVARTIS AG (CH) | 2000-04-12 | — | — | CN | disclosed |
| EP-0966461-A1 | PYRAZOLE DERIVATIVES AS HERBICIDES | Novartis AG (CH) | 1999-12-29 | — | — | EP | disclosed |
| CN-1237166-A | Pyrazole derivatives useful as herbicides | NOVARTIS AG (CH) | 1999-12-01 | — | — | CN | disclosed |
| WO-1999059990-A1 | PYRIDYL-PYRAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND THEIR USE AS HERBICIDES | NOVARTIS AG (CH) | 1999-11-25 | — | — | WO | disclosed |
| EP-0941222-A2 | PYRAZOLE DERIVATIVES USEFUL AS HERBICIDES | Novartis AG (CH) | 1999-09-15 | — | — | EP | disclosed |
| WO-1998042698-A1 | PYRAZOLE DERIVATIVES AS HERBICIDES | NOVARTIS AG (CH) | 1998-10-01 | — | — | WO | disclosed |
| WO-1998021199-A2 | PYRAZOLE DERIVATIVES USEFUL AS HERBICIDES | NOVARTIS AG (CH) | 1998-05-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150057286-A1 | NEW BIS-AMIDO PYRIDINES | SMARCC1, MKI67, SMARCC2 | KCNQ3 4215/4885KCNQ2 3912/4885KCNE1 3954/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.