Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.48 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.48 |
| ▸ | CLK2 | P49760 | 1/20 | 0.48 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | MMP14 | P50281 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | CDC7 | O00311 | 4/20 | 0.45 |
| ▸ | DBF4 | Q9UBU7 | 4/20 | 0.45 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.44 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7691089 | 0.93 | GCGR (0.48) | GCGRALDH1A1HPGDHSD17B10CSNK1A1 | |
| SCHEMBL7686215 | 0.89 | ALDH1A1 (0.51) | GCGRALDH1A1HPGDHSD17B10CSNK1A1 | |
| SCHEMBL7690467 | 0.83 | CSNK1A1 (0.60) | GCGRHSD17B10CSNK1A1CSNK1DCLK2 | |
| SCHEMBL7688692 | 0.83 | CSNK1A1 (0.69) | GCGRALDH1A1HPGDHSD17B10CSNK1A1 | |
| SCHEMBL7699114 | 0.78 | CSNK1A1 (0.51) | GCGRALDH1A1HPGDHSD17B10CSNK1A1 | |
| SCHEMBL7696380 | 0.78 | CSNK1A1 (0.62) | GCGRALDH1A1HPGDHSD17B10CSNK1A1 | |
| SCHEMBL4184780 | 0.78 | CSNK1A1 (0.62) | GCGRALDH1A1HPGDHSD17B10CSNK1A1 | |
| SCHEMBL7689435 | 0.78 | CSNK1A1 (0.61) | GCGRHSD17B10CSNK1A1CSNK1DCLK2 | |
| SCHEMBL7691339 | 0.78 | MAPT (0.59) | GCGRALDH1A1HPGDHSD17B10CSNK1A1 | |
| SCHEMBL7689130 | 0.77 | ALDH1A1 (0.57) | GCGRALDH1A1HPGDHSD17B10CDC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020049235-A1 | 3-acetyl-4-methyl-2,5-di(4-pyridyl)-1H-pyrrole, for example; treating cell adhesion molecules (CAMs) mediated diseases such as arthritis, AIDS, septic shock, cachexia, transplant rejection | PFIZER PHARMACEUTICALS INC. (JP) | 2002-04-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020049235-A1 | 3-acetyl-4-methyl-2,5-di(4-pyridyl)-1H-pyrrole, for example; treating cell adhesion molecules (CAMs) mediated diseases such as arthritis, AIDS, septic shock, cachexia, transplant rejection | ICAM1, VCAM1, CD14 | GCGR 1031/4885ALDH1A1 443/4885HPGD 1474/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.