Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 19/20 | 0.61 |
| ▸ | ACHE | P22303 | 13/20 | 0.61 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6703732 | 0.95 | HTR4 (0.58) | HTR4ACHESIGMAR1MEN1ALDH1A1 | |
| SCHEMBL2481341 | 0.87 | HTR4 (0.66) | HTR4ACHESIGMAR1MEN1ALDH1A1 | |
| SCHEMBL7682170 | 0.84 | NPC1 (0.50) | HTR4ACHESIGMAR1MEN1ALDH1A1 | |
| SCHEMBL2482136 | 0.84 | NPC1 (0.50) | HTR4ACHESIGMAR1MEN1ALDH1A1 | |
| SCHEMBL2481231 | 0.82 | NPC1 (0.48) | HTR4ACHESIGMAR1MEN1ALDH1A1 | |
| SCHEMBL27598401 | 0.81 | HTR4 (0.48) | HTR4ACHESIGMAR1MEN1ALDH1A1 | |
| SCHEMBL7688139 | 0.80 | NPC1 (0.67) | HTR4ACHEMEN1ALDH1A1KMT2A | |
| SCHEMBL7681834 | 0.79 | NPC1 (0.46) | HTR4ACHESIGMAR1MEN1ALDH1A1 | |
| SCHEMBL8575158 | 0.77 | HTR4 (0.51) | HTR4ACHEALDH1A1 | |
| SCHEMBL17709636 | 0.76 | ACHE (1.00) | HTR4ACHESIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6380230-B1 | FOR THERAPY OF DYSKINESIA, OBESITY, IRRITABLE BOWEL SYNDROME, DISEASES WHOSE TREATMENT REQUIRES STIMULATION OF THE CHOLECYSTOKININ CCK-A RECEPTORS | SANOFI-SYNTHELABO (FR) | 2002-04-30 | — | — | US | disclosed |