Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 9/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 7/20 | 0.41 |
| ▸ | FABP4 | P15090 | 2/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | FNTA | P49354 | 1/20 | 0.38 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2326863 | 0.81 | CCR2 (0.55) | CCR2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL30547718 | 0.79 | CCR2 (0.54) | CCR2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL699964 | 0.77 | CCR2 (0.65) | CCR2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL7688469 | 0.76 | CCR2 (0.56) | CCR2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL30622480 | 0.74 | CCR2 (0.61) | CCR2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL7006463 | 0.73 | CCR2 (0.60) | CCR2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL5824022 | 0.73 | HPGD (0.41) | CCR2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL2276664 | 0.71 | L3MBTL1 (0.52) | CCR2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL2322049 | 0.71 | SLC9A1 (0.48) | CCR2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL2321812 | 0.71 | CCR2 (0.48) | CCR2KDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114681443-B | Nitrile-containing antiviral compounds | 辉瑞大药厂 | 2024-05-10 | — | — | CN | disclosed |
| CN-116789648-A | Nitrile-containing antiviral compounds | 辉瑞大药厂 | 2023-09-22 | — | — | CN | disclosed |
| CN-114466838-B | Nitrile-containing antiviral compounds | 辉瑞大药厂 | 2023-05-02 | — | — | CN | disclosed |